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强直性脊柱炎的延迟诊断:一个被错失的机会?

Delayed Diagnosis of Ankylosing Spondylitis: A Missed Opportunity?

作者信息

Patel Pooja, Hussain Hira, Fahey John

机构信息

Rheumatology, Advocate Aurora Health, Brookfield, USA.

Family Medicine, St. George's University School of Medicine, Ft. Lauderdale, USA.

出版信息

Cureus. 2019 Sep 22;11(9):e5723. doi: 10.7759/cureus.5723.

Abstract

Ankylosing spondylitis is an inflammatory condition involving the axial spine, often associated with the human leukocyte antigen (HLA)-B27 genotype and supporting radiographic imaging findings. Patients develop symptomatic low back and/or hip pain beginning in late adolescence or early adulthood. Diagnosis of ankylosing spondylitis is based primarily on clinical presentation and imaging studies. In this article, we are presenting a case of a 40-year-old male patient who presented to the office with chief concerns of chronic mid-thoracic back pain and restricted range of motion of his neck. The imaging study obtained was suggestive of fusion of the sacroiliac joints. This article also highlights the presence of elevated inflammatory markers in the setting of the patients chronic symptomatic complaints which could have guided in early diagnosis.

摘要

强直性脊柱炎是一种累及中轴脊柱的炎症性疾病,常与人类白细胞抗原(HLA)-B27基因型相关,并伴有支持性的影像学检查结果。患者在青春期晚期或成年早期开始出现有症状的下背部和/或臀部疼痛。强直性脊柱炎的诊断主要基于临床表现和影像学检查。在本文中,我们介绍了一名40岁男性患者的病例,该患者因慢性胸中段背痛和颈部活动受限前来就诊。所进行的影像学检查提示骶髂关节融合。本文还强调了在患者慢性症状性主诉情况下炎症标志物升高的情况,这可能有助于早期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3168/6823060/5e689afea890/cureus-0011-00000005723-i01.jpg

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