The surface immunoglobulin receptors of human lymphocytes in pollinosis.

The immunological reaction of immediate as well as delayed type is produced in patients with pollinosis by the contact with pollen allergens. The immunological disturbances partially connected with function of T and B lymphocytes can be treated as the basal mechanism of pollinosis. The presence of surface immunoglobulins (SIg) from classes IgA, IgG and IgM on the B lymphocytes in circulating blood from the patients with pollinosis in various stages of the disease were studied. The method of direct immunofluorescence was used. The decrease of B lymphocytes with SIg of IgG was found. On the basis of presence SIg (IgA, IgG, IgM) on lymphocytes the four periods of various immunological reaction in pollinosis were differentiated: I - primary immunological response, II - secondary immunological response, III - immunological exhaust, IV - immunological stabilization.