Chessa Marco A, Patrizi Annalisa, Baraldi Carlotta, Fanti Pier Alessandro, Barisani Alessia, Vaccari Sabina
Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Dermatol Pract Concept. 2019 Oct 31;9(4):283-291. doi: 10.5826/dpc.0904a07. eCollection 2019 Oct.
Eccrine poroma (EP) is a benign adnexal neoplasm that can be pigmented in 17% of cases. Four histopathological variants of EP exist. Dermoscopically, EP can mimic many other skin neoplasms.
To provide a dermoscopic-histopathological correlation of EP, classifying the clinical and dermoscopic features of EPs on the basis of their histopathological subtype, in an attempt to better characterize these entities.
A single-center retrospective study was conducted. Clinical data were collected; patients were classified on the basis of the 4 histopathological variants of EPs. Dermoscopic images were reviewed. A dermoscopic-histopathological correlation was performed, and the results were compared with literature data.
Twenty-six lesions were included, both pigmented and nonpigmented. Three of the 4 histopathological variants were identified. Different dermoscopic features were observed for each distinct histopathological subtype of EP. The lesions mimicked different types of other skin neoplasms, in particular: nonpigmented hidroacanthoma simplex resembled nonmelanoma skin cancer; pigmented hidroacanthoma simplex appeared like a seborrheic keratosis or a solar lentigo; EPs sensu stricto presented as pink nodules if nonpigmented and were similar to seborrheic keratosis if pigmented; dermal duct tumors appeared as pigmented nodular lesions.
Distinct dermoscopic features appeared to be recurrent in each histopathological variant. Dermoscopy can provide important clues for the diagnosis of EP; the final diagnosis is allowed by histopathology. To achieve a correct diagnosis of EP, because of its clinical and dermoscopic variability, surgical excision is recommended.
小汗腺汗孔瘤（EP）是一种良性附属器肿瘤，17%的病例可出现色素沉着。EP存在四种组织病理学变异型。在皮肤镜下，EP可模仿许多其他皮肤肿瘤。
提供EP的皮肤镜-组织病理学相关性，根据其组织病理学亚型对EP的临床和皮肤镜特征进行分类，以更好地表征这些实体。
进行了一项单中心回顾性研究。收集临床数据；根据EP的4种组织病理学变异型对患者进行分类。回顾皮肤镜图像。进行皮肤镜-组织病理学相关性分析，并将结果与文献数据进行比较。
纳入26个病变，包括色素沉着和无色素沉着的病变。识别出4种组织病理学变异型中的3种。每种不同的EP组织病理学亚型观察到不同的皮肤镜特征。这些病变模仿了不同类型的其他皮肤肿瘤，特别是：无色素沉着的单纯性汗腺棘皮瘤类似于非黑素瘤皮肤癌；色素沉着的单纯性汗腺棘皮瘤看起来像脂溢性角化病或日光性雀斑样痣；狭义的EP无色素沉着时表现为粉红色结节，色素沉着时类似于脂溢性角化病；真皮导管瘤表现为色素沉着的结节性病变。
每种组织病理学变异型似乎都反复出现独特的皮肤镜特征。皮肤镜可为EP的诊断提供重要线索；最终诊断需依靠组织病理学。由于EP的临床和皮肤镜表现具有变异性，为实现正确诊断，建议手术切除。
