Basile J J, McCullough D L, Harrison L H, Dyer R B
Section of Urology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
J Urol. 1988 Nov;140(5):938-43. doi: 10.1016/s0022-5347(17)41893-3.
Acquired renal cystic disease is a recently recognized disease entity that primarily afflicts patients on chronic hemodialysis. The incidence of acquired renal cystic disease in patients with end stage renal disease ranges from 30 to 95 per cent. The major complications of acquired renal cystic disease appear to be neoplasia and hemorrhage. Neoplasia has been demonstrated in up to 45 per cent of all end stage kidneys with acquired cystic disease. Our surgical experience with 7 cases of end stage renal disease is reported. Acquired renal cystic disease was noted in 4 of the 7 cases (57 per cent) and renal neoplasia was evident in all 7. Worldwide experience to date in combined pathology and radiology series of patients undergoing hemodialysis demonstrates that acquired cystic disease, "tumor" (usually adenoma or oncocytoma) and renal carcinoma occur at respective rates of 47.1, 4.8 and 1.5 per cent. Since the pathologist will detect more tumors and cysts than the radiologist, these figures probably are an underestimate of the true incidence. Long-term surveillance of patients harboring end stage kidneys is recommended beginning with a baseline ultrasound.
获得性肾囊肿病是一种最近才被认识的疾病实体，主要折磨慢性血液透析患者。终末期肾病患者中获得性肾囊肿病的发病率在30%至95%之间。获得性肾囊肿病的主要并发症似乎是肿瘤形成和出血。在所有患有获得性囊肿病的终末期肾脏中，高达45%的病例已证实存在肿瘤形成。本文报告了我们对7例终末期肾病患者的手术经验。7例中有4例（57%）发现有获得性肾囊肿病，所有7例均有明显的肾肿瘤形成。迄今为止，全球范围内对接受血液透析患者的病理学和放射学联合系列研究表明，获得性囊肿病、“肿瘤”（通常为腺瘤或嗜酸细胞瘤）和肾癌的发生率分别为47.1%、4.8%和1.5%。由于病理学家比放射科医生能检测到更多的肿瘤和囊肿，这些数字可能低估了实际发病率。建议对患有终末期肾脏的患者从基线超声检查开始进行长期监测。
