Konishi F, Mukawa A, Kitada H
Acta Pathol Jpn. 1980 Sep;30(5):847-58. doi: 10.1111/j.1440-1827.1980.tb00977.x.
Four surgical cases of acquired cystic disease of the kidney in the third decade are reported, which include renal cell carcinoma in three patients and multiple adenomas and cystadenomas in all patients. The intervening parenchyma of these kidneys was disorganized as end stage kidney and numerous cysts were found in both kidneys. Some of the cysts were lined by hyperplastic epithelium consisting of clear and granular cells arranged in piled up and papillary fashion. These cysts were diagnosed as cystadenoma. Multiple solid adenomas of a 28-year-old male on hemodialysis for 6 years were of various size as if arranged in developing stage of the growth. Summing up all cases included in the literature, the mean duration of hemodialysis of the cases with renal tumor was 5.2 years, while 2.9 years without tumor. With increase of duration of hemodialysis, acquired cystic disease of the kidney is exposed to a high risk of developing malignancy.
报告了4例发生于第三个十年的获得性肾囊肿病的外科病例，其中3例患者患有肾细胞癌，所有患者均有多发腺瘤和囊腺瘤。这些肾脏的中间实质呈终末期肾组织紊乱，双侧肾脏均发现大量囊肿。部分囊肿内衬增生上皮，由透明细胞和颗粒细胞组成，呈堆积状和乳头状排列。这些囊肿被诊断为囊腺瘤。一名接受6年血液透析的28岁男性患者的多发实性腺瘤大小各异，似乎处于生长发育阶段。总结文献中纳入的所有病例，发生肾肿瘤的病例血液透析平均时长为5.2年，无肿瘤的病例为2.9年。随着血液透析时长的增加，获得性肾囊肿病发生恶性病变的风险增高。
