Kim Youn-Jung, Bae Jun-Il, Ryoo Seung Mok, Kim Won Young
Department of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Acute Crit Care. 2019 May;34(2):165-169. doi: 10.4266/acc.2017.00045. Epub 2018 Nov 7.
The inactivated influenza vaccination is generally safe with mostly mild side effects. We report a rare but fatal adverse event following influenza vaccination. A previously healthy 27-year-old woman who received the influenza vaccination 3 days before presenting to the emergency department had rapidly aggravating dyspnea and mental deterioration. She was diagnosed as having acute fulminant myocarditis with refractory cardiogenic shock, which was successfully managed with veno-arterial extracorporeal membrane oxygenation. The cardiac function of the patient recovered in 3 weeks.
灭活流感疫苗一般是安全的，副作用大多较轻。我们报告了1例流感疫苗接种后罕见的致命不良事件。1名27岁既往健康的女性在前往急诊科就诊前3天接种了流感疫苗，随后出现呼吸困难迅速加重和精神状态恶化。她被诊断为急性暴发性心肌炎伴难治性心源性休克，通过静脉-动脉体外膜肺氧合成功治疗。患者的心脏功能在3周内恢复。
