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一名儿童严重钝性创伤性肺损伤后的长期体外膜肺氧合治疗

Long-term extracorporeal membrane oxygenation after severe blunt traumatic lung injury in a child.

作者信息

Lee Ok Jeong, Cho Yang Hyun, Hwang Jinwook, Yoon Inae, Kim Young-Ho, Cho Joongbum

机构信息

Department of Pediatrics, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea.

Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Acute Crit Care. 2019 Aug;34(3):223-227. doi: 10.4266/acc.2016.00472. Epub 2017 Feb 10.

DOI:10.4266/acc.2016.00472
PMID:31723933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6849020/
Abstract

Managing acute respiratory distress syndrome (ARDS) after severe blunt traumatic lung injury can be challenging. In cases where patients are refractory to conventional therapy, extracorporeal membrane oxygenation (ECMO) should be considered. In addition, the heparin-coated circuit can reduce hemorrhagic complications in patients with multiple traumas. Although prolonged ECMO may be necessary, excellent outcomes are frequently associated. In this study, we report long-term support with venovenous-ECMO applied in a child with severe blunt trauma in Korea. This 10-year-old and 30 kg male with severe blunt thoracic trauma after a car accident developed severe ARDS a few days later, and ECMO was administered for 33 days. Because of pulmonary hemorrhage during ECMO support, heparin was stopped for 3 days and then restarted. He was weaned from ECMO successfully and has been able to run without difficulty for the 2 years since discharge.

摘要

管理严重钝性创伤性肺损伤后的急性呼吸窘迫综合征(ARDS)具有挑战性。在患者对传统治疗无效的情况下,应考虑体外膜肺氧合(ECMO)。此外,肝素涂层回路可减少多发伤患者的出血并发症。尽管可能需要长时间使用ECMO,但通常会有良好的预后。在本研究中,我们报告了在韩国一名严重钝性创伤儿童中应用静脉-静脉ECMO进行长期支持的情况。这名10岁、体重30公斤的男性在车祸后发生严重钝性胸部创伤,几天后发展为严重ARDS,并接受了33天的ECMO治疗。由于ECMO支持期间发生肺出血,肝素停用了3天,然后重新开始使用。他成功撤机,出院后2年来能够毫无困难地跑步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/6849020/8c4a7cee801f/acc-2016-00472f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/6849020/861e6b51cc79/acc-2016-00472f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/6849020/1ef379c55540/acc-2016-00472f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/6849020/8c4a7cee801f/acc-2016-00472f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/6849020/861e6b51cc79/acc-2016-00472f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/6849020/1ef379c55540/acc-2016-00472f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/6849020/8c4a7cee801f/acc-2016-00472f3.jpg

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Venovenous extracorporeal life support for posttraumatic respiratory distress syndrome in adults: the risk of major hemorrhages.成人创伤后呼吸窘迫综合征的静脉-静脉体外生命支持:大出血风险
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Acute respiratory distress syndrome: the Berlin Definition.
急性呼吸窘迫综合征:柏林定义。
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J Trauma Acute Care Surg. 2012 May;72(5):1444-7. doi: 10.1097/TA.0b013e31824d68e3.
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Extracorporeal membrane oxygenation in severe trauma patients with bleeding shock.体外膜肺氧合在伴有出血性休克的严重创伤患者中的应用。
Resuscitation. 2010 Jul;81(7):804-9. doi: 10.1016/j.resuscitation.2010.02.020. Epub 2010 Apr 7.
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Extracorporeal membrane oxygenation in adults with severe respiratory failure: a multi-center database.体外膜肺氧合在成人严重呼吸衰竭中的应用:多中心数据库研究。
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