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一名患TINU综合征的患者出现双侧结节性前巩膜炎与大血管动脉炎共病。

Co-occurrence of bilateral nodular anterior scleritis and large-vessel arteritis in a patient with TINU syndrome.

作者信息

Zonnevylle Kirsten, Schauwvlieghe Pieter-Paul, Van Calster Joachim, Lenaerts Jan, Peeters Domien

机构信息

Ophthalmology, University Hospitals Leuven, Belgium.

Department of Rheumatology, University Hospitals Leuven, KU Leuven, Belgium.

出版信息

GMS Ophthalmol Cases. 2019 Oct 25;9:Doc34. doi: 10.3205/oc000123. eCollection 2019.

Abstract

We present a case of tubulointerstitial nephritis and uveitis (TINU) with nodular anterior scleritis and large-vessel arteritis. A 67-year-old patient was admitted to the hospital with high fever, thoracic pain, and weakness. Bilateral anterior uveitis was seen at that time. Laboratory examination showed acute renal failure. A renal biopsy was performed and showed pathognomonic signs of tubulointerstitial nephritis (TIN). Six months later, she developed ocular inflammation suggestive of nodular scleritis. One year after hospital admission, she presented with large-vessel arteritis. We describe a case of TINU with co-occurrence of scleritis and large-vessel arteritis.

摘要

我们报告一例伴有结节性前巩膜炎和大血管动脉炎的肾小管间质性肾炎和葡萄膜炎(TINU)。一名67岁患者因高热、胸痛和乏力入院。当时可见双侧前葡萄膜炎。实验室检查显示急性肾衰竭。进行了肾活检,显示出肾小管间质性肾炎(TIN)的特征性体征。6个月后,她出现提示结节性巩膜炎的眼部炎症。入院1年后,她出现了大血管动脉炎。我们描述了一例同时发生巩膜炎和大血管动脉炎的TINU病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f75/6839028/70b168cb6b4b/OC-09-34-g-001.jpg

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本文引用的文献

1
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Mechanisms of Drug-Induced Interstitial Nephritis.药物性间质性肾炎的发病机制
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