小儿急性呼吸窘迫综合征（PARDS）患儿的镇静策略
Sedation strategies in children with pediatric acute respiratory distress syndrome (PARDS).
作者信息
Rosenberg Lynne, Traube Chani
机构信息
Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA.
出版信息
Ann Transl Med. 2019 Oct;7(19):509. doi: 10.21037/atm.2019.09.16.
Abstract
In this review, we discuss the changing landscape of sedation in mechanically ventilated children with pediatric acute respiratory distress syndrome (PARDS). While previous approaches advocated for early and deep sedation with benzodiazepines, emerging literature has highlighted the benefits of light sedation and use of non-benzodiazepine sedating agents, such as dexmedetomidine. Recent studies have emphasized the importance of monitoring multiple factors including, but not limited to, sedation depth, analgesia efficacy, opiate withdrawal, and development of delirium. Through this approach, we hope to improve PARDS outcomes. Overall, more research is needed to further our understanding of the best sedation strategies in children with PARDS.
摘要
在本综述中，我们讨论了小儿急性呼吸窘迫综合征（PARDS）机械通气患儿镇静情况的变化。虽然以往的方法主张早期使用苯二氮䓬类药物进行深度镇静，但新出现的文献强调了浅镇静以及使用右美托咪定等非苯二氮䓬类镇静剂的益处。最近的研究强调了监测多个因素的重要性，这些因素包括但不限于镇静深度、镇痛效果、阿片类药物戒断以及谵妄的发生。通过这种方法，我们希望改善PARDS的治疗结果。总体而言，需要更多的研究来进一步了解PARDS患儿的最佳镇静策略。
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