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老年癌症患者的疼痛管理。

Managing Pain in the Older Cancer Patient.

机构信息

Department of Anaesthesia, Mater Misericordiae University Hospital, Level 4, Whitty Building, Eccles Street, Dublin, D07 R2WY, Ireland.

出版信息

Curr Oncol Rep. 2019 Nov 14;21(11):100. doi: 10.1007/s11912-019-0854-7.

DOI:10.1007/s11912-019-0854-7
PMID:31728653
Abstract

PURPOSE OF REVIEW

This paper aims to give the specialist and non-specialist alike an overview of the considerations involved in the management of cancer-related pain in the older population.

RECENT FINDINGS

Comprehensive guidelines on cancer pain management have been published recently by expert bodies. Cancer pain differs in many respects to other pain conditions and we are likely to encounter it more frequently in older patients in the future. The elderly are more sensitive to the effects of many analgesic medications. The elderly patient with cancer pain presents a unique challenge to the treating physician. The biological effects of ageing impact on the efficacy of many pain management strategies as well as its diagnosis and assessment. Treatment options can be broadly divided into pharmacological, non-pharmacological and interventional. A multidisciplinary approach and frequent re-assessment are essential in achieving favourable outcomes in this patient group.

摘要

目的综述

本文旨在为专业人士和非专业人士提供老年人癌症相关疼痛管理中需要考虑的问题的概述。

最近的发现

最近,专家机构已经发布了关于癌症疼痛管理的综合指南。癌症疼痛在许多方面与其他疼痛状况不同,我们将来可能会在老年患者中更频繁地遇到这种情况。老年人对许多镇痛药物的作用更为敏感。患有癌症疼痛的老年患者对治疗医生提出了独特的挑战。衰老的生物学效应会影响许多疼痛管理策略的疗效及其诊断和评估。治疗选择可以大致分为药物治疗、非药物治疗和介入治疗。在实现这组患者的良好结果方面,多学科方法和频繁的重新评估是必不可少的。

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本文引用的文献

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Efficacy of Superior Hypogastric Plexus Neurolysis for the Treatment of Cancer-Related Pelvic Pain.上腹下丛神经松解术治疗癌性盆腔疼痛的疗效
Pain Med. 2020 Jun 1;21(6):1255-1262. doi: 10.1093/pm/pnz151.
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The efficacy of the ganglion impar block in perineal and pelvic cancer pain.阴部和骨盆癌痛的脊神经节丛阻滞的疗效。
Support Care Cancer. 2019 Nov;27(11):4327-4330. doi: 10.1007/s00520-019-04738-9. Epub 2019 Mar 18.
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Percutaneous Neurolysis for Pain Management in Oncological Patients.经皮神经松解术在肿瘤患者疼痛管理中的应用。
多模式跨专业成人癌症疼痛管理:一项综合综述。
Oncol Nurs Forum. 2024 Dec 12;52(1):41-50. doi: 10.1188/25.ONF.41-50.
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Fentanyl in cancer pain management: avoiding hasty judgments and discerning its potential benefits.芬太尼在癌症疼痛管理中的应用:避免仓促判断并识别其潜在益处。
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Multidisciplinary management of chronic pain in elderly oncology patients.老年肿瘤患者慢性疼痛的多学科管理
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Exclusion of older adults from clinical trials in cancer-related pain.癌症相关疼痛临床试验中排除老年人。
Front Med (Lausanne). 2022 Aug 4;9:945481. doi: 10.3389/fmed.2022.945481. eCollection 2022.
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4
Management of cancer pain in adult patients: ESMO Clinical Practice Guidelines.成年患者癌痛的管理:ESMO临床实践指南
Ann Oncol. 2018 Oct 1;29(Suppl 4):iv166-iv191. doi: 10.1093/annonc/mdy152.
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Oral Ketamine vs Placebo in Patients With Cancer-Related Neuropathic Pain: A Randomized Clinical Trial.癌症相关性神经病理性疼痛患者口服氯胺酮与安慰剂的随机临床试验。
JAMA Oncol. 2018 Jun 1;4(6):870-872. doi: 10.1001/jamaoncol.2018.0131.
6
Retrospective Analysis of Intrathecal Drug Delivery: Outcomes, Efficacy, and Risk for Cancer-Related Pain at a High Volume Academic Medical Center.高容量学术医学中心鞘内药物递送的回顾性分析:癌症相关疼痛的结局、疗效和风险
Neuromodulation. 2018 Oct;21(7):660-663. doi: 10.1111/ner.12759. Epub 2018 Feb 14.
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Oral paracetamol (acetaminophen) for cancer pain.口服对乙酰氨基酚用于癌症疼痛。
Cochrane Database Syst Rev. 2017 Jul 12;7(7):CD012637. doi: 10.1002/14651858.CD012637.pub2.
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Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer pain in adults.用于成人癌痛的口服非甾体抗炎药(NSAIDs)。
Cochrane Database Syst Rev. 2017 Jul 12;7(7):CD012638. doi: 10.1002/14651858.CD012638.pub2.
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Ketamine as an adjuvant to opioids for cancer pain.氯胺酮作为阿片类药物治疗癌痛的辅助用药。
Cochrane Database Syst Rev. 2017 Jun 28;6(6):CD003351. doi: 10.1002/14651858.CD003351.pub3.
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Evaluation of intrathecal drug delivery system for intractable pain in advanced malignancies: A prospective cohort study.鞘内药物输送系统用于晚期恶性肿瘤顽固性疼痛的评估:一项前瞻性队列研究。
Medicine (Baltimore). 2017 Mar;96(11):e6354. doi: 10.1097/MD.0000000000006354.