Research and Graduate Studies in Food Science, School of Chemistry, Universidad Autónoma de Querétaro, C.U., Cerro de las Campanas S/N, Queretaro 76010, Mexico.
Research and Graduate Studies in Food Science, School of Chemistry, Universidad Autónoma de Querétaro, C.U., Cerro de las Campanas S/N, Queretaro 76010, Mexico.
Food Res Int. 2019 Dec;126:108589. doi: 10.1016/j.foodres.2019.108589. Epub 2019 Jul 27.
The aim of the present study was to evaluate extractable (EPP), non-extractable polyphenols (NEPP) and organic acid in Roselle by-product, as well as its potential health beneficial effects in obesity control and their complication in rats fed with high caloric diet. Roselle by-product showed a higher content of dietary fiber and NEPP than Roselle calix, which was was a better source of EPP (P < .05). The UPLC-QTOF MS analysis allowed the tentative identification of 34 EPP, and 3 hydrolysable polyphenols (NEPP), and 2 organic acids in calyx and by-product. Rats fed with a high caloric diet supplemented with 4% of dietary fiber from by-products and Roselle calyx powder generated a reduction in body weight gain (10% and 14%), adipocytes hypertrophy (17% and 13%) and insulin resistance (48% and 59%) and hepatic steatosis (15% and 25%; respectively) compared with rats fed with a high caloric diet alone. Interestingly, even though Roselle by-product has low EPP contents showed comparable beneficial health effects than Roselle calyces. These effects could be associated with high content of dietary fiber and NEPP. Together, the results of the present study indicate that Roselle by-products could be a potential ingredient to develop functional foods against obesity and its complications.
本研究旨在评估玫瑰茄副产物中的可提取多酚（EPP）、不可提取多酚（NEPP）和有机酸，以及其在控制肥胖及其并发症方面的潜在健康益处，方法是用高卡路里饮食喂养大鼠。玫瑰茄副产物的膳食纤维和 NEPP 含量均高于玫瑰茄花萼，EPP 含量更高（P<0.05）。UPLC-QTOF MS 分析允许对萼片和副产物中的 34 种 EPP、3 种可水解多酚（NEPP）和 2 种有机酸进行推测性鉴定。与单独用高卡路里饮食喂养的大鼠相比，用添加 4%副产物和玫瑰茄花萼粉膳食纤维的高卡路里饮食喂养的大鼠体重增加减少（10%和 14%）、脂肪细胞肥大减少（17%和 13%）、胰岛素抵抗减少（48%和 59%）和肝脂肪变性减少（15%和 25%）。有趣的是，尽管玫瑰茄副产物的 EPP 含量较低，但仍显示出与玫瑰茄花萼相当的健康益处。这些作用可能与高膳食纤维和 NEPP 含量有关。总之，本研究结果表明，玫瑰茄副产物可能是开发针对肥胖及其并发症的功能性食品的潜在成分。
