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洛神花( Hibiscus sabdariffa )对肥胖的主要有益作用不仅与其花色苷含量有关。

The main beneficial effect of roselle (Hibiscus sabdariffa) on obesity is not only related to its anthocyanin content.

机构信息

DIPA-Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico.

CICATA - Querétaro, Instituto Politécnico Nacional, Querétaro, Mexico.

出版信息

J Sci Food Agric. 2019 Jan 30;99(2):596-605. doi: 10.1002/jsfa.9220. Epub 2018 Aug 9.

DOI:10.1002/jsfa.9220
PMID:29943479
Abstract

BACKGROUND

The calyxes of roselle (Hibiscus sabdariffa) are recognized for their high nutraceutical value because they decrease body weight and obesity complications. These effects have been attributed mainly to anthocyanins. However, the calyxes comprise important concentration of flavonoids, phenolic, and organic acids, which could also contribute to these effects. The objective of this work was to determine the effect of the Alma Blanca white roselle variety on obesity and hepatic steatosis in high-fat, high-fructose, diet-fed rats and compare its beneficial effects with the red variety (Criolla), which has been more extensively studied.

RESULTS

Aqueous and methanolic extracts were prepared from two roselle varieties, Alma Blanca (white) and Criolla (red). The phytochemical profiles were determined using high-performance liquid chromatography-mass spectrometry (HPLC-MS). Criolla extracts contain principally anthocyanins, phenolic acids, and flavonoids. Anthocyanins were not detected in Alma Blanca. The aqueous extracts of both varieties prevented body-weight gain and decreased adipocytes hyperplasia on rats fed a hypercaloric diet. These extracts also protected against hepatic steatosis. These benefits were associated with hibiscus, dimethyl hibiscus, and hydroxycitric acid.

CONCLUSION

These results demonstrated that calyxes from Hibiscus sabdariffa contain compounds that are different from anthocyanins, with potential benefits to health. The organic acids were strongly associated with these beneficial health effects. © 2018 Society of Chemical Industry.

摘要

背景

洛神花的花萼因其具有降低体重和肥胖并发症的高营养价值而受到认可。这些作用主要归因于花色苷。然而,花萼还含有重要浓度的类黄酮、酚类和有机酸,这也可能有助于这些作用。本工作的目的是确定 Alma Blanca 白色洛神花品种对高脂肪、高果糖饮食喂养的大鼠肥胖和肝脂肪变性的影响,并将其与已广泛研究的红色品种(Criolla)的有益效果进行比较。

结果

从 Alma Blanca(白色)和 Criolla(红色)两种洛神花品种中制备了水提物和甲醇提取物。采用高效液相色谱-质谱联用(HPLC-MS)法测定植物化学成分。 Criolla 提取物主要含有花色苷、酚酸和类黄酮。在 Alma Blanca 中未检测到花色苷。两种品种的水提取物均可预防高热量饮食喂养大鼠体重增加,并减少脂肪细胞增生。这些提取物还可预防肝脂肪变性。这些益处与洛神花、二甲基洛神花和羟基柠檬酸有关。

结论

这些结果表明,洛神花花萼含有与花色苷不同的化合物,对健康具有潜在益处。有机酸与这些有益的健康作用密切相关。 © 2018 英国化学学会。

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