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YAP1-fusions in pediatric NF2-wildtype meningioma.

作者信息

Sievers Philipp, Chiang Jason, Schrimpf Daniel, Stichel Damian, Paramasivam Nagarajan, Sill Martin, Gayden Tenzin, Casalini Belen, Reuss David E, Dalton James, Pajtler Kristian W, Hänggi Daniel, Herold-Mende Christel, Rushing Elisabeth, Korshunov Andrey, Mawrin Christian, Weller Michael, Schlesner Matthias, Wick Wolfgang, Jabado Nada, Jones David T W, Pfister Stefan M, von Deimling Andreas, Ellison David W, Sahm Felix

机构信息

Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

出版信息

Acta Neuropathol. 2020 Jan;139(1):215-218. doi: 10.1007/s00401-019-02095-9. Epub 2019 Nov 16.

DOI:
10.1007/s00401-019-02095-9
PMID:31734728
Abstract
摘要

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YAP1-fusions in pediatric NF2-wildtype meningioma.小儿NF2野生型脑膜瘤中的YAP1融合基因
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Lead exposure promotes NF2-wildtype meningioma cell proliferation through the Merlin-Hippo signaling pathway.铅暴露通过Merlin-Hippo信号通路促进NF2野生型脑膜瘤细胞增殖。
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