Suppr超能文献

一种用于指导设计具有特定腹壁疝所需机械性能的外科补片的数值方法。

A numerical method for guiding the design of surgical meshes with suitable mechanical properties for specific abdominal hernias.

机构信息

Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China.

Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China; Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability, National Research Center for Rehabilitation Technical Aids, Beijing, 100176, China.

出版信息

Comput Biol Med. 2020 Jan;116:103531. doi: 10.1016/j.compbiomed.2019.103531. Epub 2019 Nov 9.

Abstract

Abdominal hernia is a common disease, and the most effective treatment of it is using surgical meshes. However, it was found that due to the mismatch of the mechanical properties between the mesh and the tissues around the hernia, there was still a recurrence rate of more than 33% and a high probability of postoperative discomfort. Currently, because of the complex mechanical environment provided by the abdominal tissues and the lack of quantitative research, it is still difficult to select a mesh with suitable mechanical properties for a hernia with specific position and size. Therefore, the purpose of this study is to use numerical models to evaluate the mechanical behavior of both abdominal wall and meshes after repair, and to determine the most suitable mechanical properties of meshes for specific hernias, including elastic modulus and tensile strength. To realize that purpose, defects with different locations and sizes were considered, including defects of 20 mm and 40 mm in diameter on linea alba (LA20 and LA40) and on rectus abdominis (RA20 and RA40), and laparoscopic repair was simulated. The mechanical properties of the most suitable mesh we determined are as follows: suitable modulus for LA20, LA40, RA20 and RA40 are 1 MPa, 3 MPa, 2 MPa and 4 MPa, respectively; suitable tensile strength for LA20, LA40, RA20 and RA40 are 0.35 MPa, 0.89 MPa, 0.77 MPa and 1.43 MPa, respectively. These data could give a standard of mechanical properties which can be referenced in mesh design and evaluation and provide surgeons with treatment advice for specific patients.

摘要

腹壁疝是一种常见疾病,最有效的治疗方法是使用外科补片。然而,人们发现,由于补片与疝周围组织的机械性能不匹配,仍然存在 33%以上的复发率和术后不适的高概率。目前,由于腹部组织提供的复杂机械环境和缺乏定量研究,仍然难以为具有特定位置和大小的疝选择具有合适机械性能的补片。因此,本研究的目的是使用数值模型评估修复后腹壁和补片的力学行为,并确定最适合特定疝的补片的机械性能,包括弹性模量和拉伸强度。为了实现这一目的,考虑了不同位置和大小的缺陷,包括白线(LA20 和 LA40)和腹直肌(RA20 和 RA40)上直径为 20mm 和 40mm 的缺陷,并模拟了腹腔镜修复。我们确定的最适合的补片机械性能如下:LA20、LA40、RA20 和 RA40 的合适模量分别为 1MPa、3MPa、2MPa 和 4MPa;LA20、LA40、RA20 和 RA40 的合适拉伸强度分别为 0.35MPa、0.89MPa、0.77MPa 和 1.43MPa。这些数据可为补片设计和评估提供机械性能标准,并为特定患者的外科医生提供治疗建议。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验