Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Center for Spine Health, Cleveland Clinic, Desk S40, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Neurosurg Clin N Am. 2020 Jan;31(1):57-64. doi: 10.1016/j.nec.2019.08.007. Epub 2019 Oct 24.
Patients with symptomatic instability of the spine may be treated surgically with interbody fusion. Cost and complexity in this procedure arises owing to the implanted materials involved with facilitating fusion such as titanium or polyetheretherketone. Surface modifications have been developed to augment these base materials such as plasma-spraying polyetheretherketone with titanium or coating implants with hydroxyapatite. Although some evidence has been gathered on these novel materials, additional study is needed to establish the true efficacy of surface modifications for interbody fusion devices in improving long-term patient outcomes.
对于有脊柱症状性不稳定性的患者，可采用椎间融合术进行手术治疗。由于钛或聚醚醚酮等促进融合的植入材料的成本和复杂性，该手术的费用和复杂性增加。已经开发了表面改性来增强这些基础材料，例如等离子喷涂聚醚醚酮与钛或羟基磷灰石涂层植入物。尽管已经收集了一些关于这些新型材料的证据，但需要进一步的研究来确定表面改性对改善长期患者预后的椎间融合装置的真正疗效。
