一种用于治疗阴道感染的新型多草药组合的抗菌活性。
Antimicrobial activity of a novel polyherbal combination for the treatment of vaginal infection.
作者信息
Yadav Shiv Kumar, Jain Gaurav K, Mazumder Avijit, Khar Roop K
机构信息
Department of Pharmacognosy, B. S. Anangpuria Institute of Pharmacy, Faridabad, Haryana, India.
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
出版信息
J Adv Pharm Technol Res. 2019 Oct-Dec;10(4):190-194. doi: 10.4103/japtr.JAPTR_3_19.
The present study evaluated the antimicrobial activity of (AI), (CI), and (TFG) against bacterial and fungal pathogens responsible for the vaginal infections. The AI, CI, and TFG were selected to include antimicrobial and antifungal action against wide range of microbes. The different extracts of the herbs were evaluated for antibacterial and antifungal activity by well diffusion assays. Based on the results, the combination was selected and evaluated, "polyherbal antimicrobial (PHA)." The developed PHA extract demonstrated synergistic broad-spectrum antimicrobial activities including antibacterial and antifungal activity (minimum inhibition concentration: 5-7 mg/ml).
本研究评估了芦荟（AI）、肉桂（CI）和姜黄（TFG）对引起阴道感染的细菌和真菌病原体的抗菌活性。选择AI、CI和TFG是为了使其对多种微生物具有抗菌和抗真菌作用。通过打孔扩散法评估了这些草药的不同提取物的抗菌和抗真菌活性。根据结果，选择并评估了“多草药抗菌剂（PHA）”。所开发的PHA提取物表现出协同的广谱抗菌活性，包括抗菌和抗真菌活性（最低抑菌浓度：5 - 7毫克/毫升）。
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