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纵隔血管淋巴管畸形酷似胸腺癌。

Mediastinal venolymphatic malformations mimicking thymic carcinoma.

机构信息

Department of Thoracic and Cardiovascular Surgery, Haeundae Paik Hospital, Busan, South Korea.

Department of Pathology, Inje University College of Medicine, Busan, South Korea.

出版信息

Thorac Cancer. 2020 Jan;11(1):170-172. doi: 10.1111/1759-7714.13239. Epub 2019 Nov 19.

DOI:10.1111/1759-7714.13239
PMID:31742877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6938752/
Abstract

This report was about a 60-year-old asymptomatic female patient who presented to our clinic with an anterior mediastinal mass found on routine chest computed tomography (CT). Chest CT revealed an irregular poorly enhanced anterior mediastinal mass which showed signs of infiltration to adjacent structures with sparse calcifications. The preliminary diagnosis was thymic carcinoma. The patient underwent extended thymectomy via median sternotomy and complete excision of the tumor. A small draining vein to the left brachiocephalic vein and phleboliths were identified in the tumor. A definitive diagnosis was made of mediastinal venolymphatic malformation (VLM). The patient had an uneventful clinical course and was discharged without further complication. This report highlights that it is possible to misdiagnose mediastinal VLM as thymic carcinoma and could serve as a useful reminder to physicians in the future.

摘要

本报告介绍了一位 60 岁无症状女性患者,因常规胸部计算机断层扫描(CT)发现前纵隔肿块而就诊于我院。胸部 CT 显示不规则、不均匀强化的前纵隔肿块,有向邻近结构浸润的迹象,伴有稀疏的钙化。初步诊断为胸腺癌。患者接受了正中胸骨切开术的广泛胸腺切除术和肿瘤完全切除术。在肿瘤中发现了一条通向左侧头臂静脉的小引流静脉和静脉石。最终诊断为纵隔静脉淋巴管畸形(VLM)。患者的临床病程顺利,无进一步并发症出院。本报告强调,纵隔 VLM 可能被误诊为胸腺癌,这可能对未来的医生有所帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/6938752/aa07d2951b36/TCA-11-170-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/6938752/c43d511012a0/TCA-11-170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/6938752/aa07d2951b36/TCA-11-170-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/6938752/c43d511012a0/TCA-11-170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/6938752/aa07d2951b36/TCA-11-170-g002.jpg

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本文引用的文献

1
Lymphatic and venous malformation or "lymphangiohemangioma" of the anterior mediastinum: case report and literature review.前纵隔淋巴管瘤和静脉畸形或“淋巴管血管瘤”:病例报告及文献综述
Gen Thorac Cardiovasc Surg. 2011 Aug;59(8):575-8. doi: 10.1007/s11748-010-0719-3. Epub 2011 Aug 18.
2
Intratumoural lymphatics in benign and malignant soft tissue tumours.良性和恶性软组织肿瘤中的瘤内淋巴管
Virchows Arch. 2008 Nov;453(5):457-64. doi: 10.1007/s00428-008-0660-3. Epub 2008 Sep 24.
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Molecular pathogenesis of vascular anomalies: classification into three categories based upon clinical and biochemical characteristics.
血管异常的分子发病机制:基于临床和生化特征分为三类
Lymphat Res Biol. 2003;1(4):267-81. doi: 10.1089/153968503322758076.
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Hemangiomas, vascular malformations, and lymphovenous malformations: classification and methods of treatment.血管瘤、血管畸形和淋巴管静脉畸形:分类与治疗方法
Plast Reconstr Surg. 1993 Jun;91(7):1216-30. doi: 10.1097/00006534-199306000-00006.
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Lymphatic-venous malformation (lymphangiohemangioma) of mediastinum.纵隔淋巴管静脉畸形(淋巴管血管瘤)
J Comput Assist Tomogr. 1983 Oct;7(5):895-7. doi: 10.1097/00004728-198310000-00028.