我们应该为不明原因复发性流产的夫妇提供体外受精吗？
Should We Offer In Vitro Fertilization to Couples with Unexplained Recurrent Pregnancy Loss?
作者信息
Kirshenbaum Michal, Orvieto Raoul
机构信息
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan 52621, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 39040, Israel.
出版信息
J Clin Med. 2019 Nov 16;8(11):2001. doi: 10.3390/jcm8112001.
Abstract
In clinical practice, empirical treatments are often offered to couples with recurrent pregnancy loss, including in vitro fertilization. Given that most patients with recurrent pregnancy loss are fertile, the scientific rationale of in vitro fertilization for these couple is debatable. This review will discuss the potential benefits of using in vitro fertilization in couples with recurrent pregnancy loss, such as shortening the time to conceive, optimizing the timing of conception, improving gamete and embryo quality, endometrial receptivity and the use of "adds-on". At present, there is not enough evidence to justify IVF as a treatment option in couples with unexplained recurrent pregnancy loss.
摘要
在临床实践中，对于反复流产的夫妇通常会提供经验性治疗，包括体外受精。鉴于大多数反复流产的患者具有生育能力，体外受精用于这些夫妇的科学依据存在争议。本综述将讨论体外受精用于反复流产夫妇的潜在益处，如缩短受孕时间、优化受孕时机、改善配子和胚胎质量、子宫内膜容受性以及“附加治疗”的应用。目前，尚无足够证据证明体外受精可作为不明原因反复流产夫妇的一种治疗选择。
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