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本文引用的文献

1
Partial ossicular reconstruction: comparison of three different prostheses in clinical and experimental studies.部分听骨链重建:三种不同假体在临床和实验研究中的比较
Otol Neurotol. 2009 Apr;30(3):332-8. doi: 10.1097/MAO.0b013e31819679dd.
2
Ossiculoplasty with intact stapes: analysis of hearing results according to the middle ear risk index.镫骨完整的鼓室成形术:根据中耳风险指数分析听力结果
Acta Otolaryngol. 2009 Oct;129(10):1088-94. doi: 10.1080/00016480802587853.
3
Ossiculoplasty using incus interposition: hearing results and analysis of the middle ear risk index.使用砧骨植入术的听骨成形术:听力结果及中耳风险指数分析
Otol Neurotol. 2005 Sep;26(5):853-8. doi: 10.1097/01.mao.0000185054.92265.b7.
4
Ossicular chain reconstruction: titanium versus plastipore.听骨链重建:钛质材料与聚氯乙烯多孔材料的比较
Laryngoscope. 2003 Oct;113(10):1731-5. doi: 10.1097/00005537-200310000-00013.
5
Extrusion rates and hearing results in ossicular reconstruction.听骨链重建中的挤压率与听力结果
Otolaryngol Head Neck Surg. 2001 Sep;125(3):135-41. doi: 10.1067/mhn.2001.117163.
6
Hearing results of ossiculoplasty in Austin-Kartush group A patients.奥斯汀-卡图什A组患者听骨成形术的听力结果。
Otol Neurotol. 2001 Mar;22(2):140-4. doi: 10.1097/00129492-200103000-00004.
7
Late results of tympanoplasty using ossicle or cortical bone.使用听小骨或皮质骨进行鼓室成形术的远期结果。
J Laryngol Otol. 1983 Jan;97(1):19-25. doi: 10.1017/s0022215100093750.

使用自体小听骨与同种异体移植物(聚四氟乙烯)进行鼓室成形术的比较。

Comparison of Ossiculoplasty Using Autograft Ossicle Versus Allograft (Teflon).

作者信息

Hajela Anupriya, Kumar Sunil, Singh H P, Verma Veerendra

机构信息

Deptartement of ENT, Head Neck Surgery, BDBA Municipal General Hospital Kandivali, Mumbai, India.

2Department of Otorhinolaryngology and Head Neck Surgery, King George's Medical University, Lucknow, UP India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 2):1309-1313. doi: 10.1007/s12070-018-1369-5. Epub 2018 Apr 19.

DOI:10.1007/s12070-018-1369-5
PMID:31750170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6841807/
Abstract

Chronic suppurative otitis media in almost any form can disrupt the integrity of ossicular chain. Various materials have been used for ossicular substitution or reconstruction, including both biologic and alloplastic materials. Teflon piston is now the most widely used prosthesis for reconstruction of the ossicular chain in cases of otosclerosis. The oto-surgeons are still confronted with problems of ossicular reconstruction regarding the surgical procedure to be done, type of graft to be selected especially in low and poor socioeconomic population. Thus, there is a need felt to comprehensively and holistically evaluate the outcome of ossiculoplasty using Autograft ossicle versus Allograft ossicle (Teflon). Total 64 patients of chronic suppurative otitis media with no active ear infection and air-bone-gap of more than 15 dB were admitted for surgery and divided into two groups according to material used for ossiculoplasty as group A (Autograft) and group B (Allograft). Patients were evaluated at 3 and 6 months post-operatively using audiogram. In both Group A and B, the average pre-operative AC was 40.62 dB (SD 9.65) and 39.37 (SD 10.53) respectively. In 3 months there was a change of 8.83% from 40.62 dB to 37.03 dB in Group-A ( < 0.109, not statistically significant) and 13.10% change from 39.37 dB to 34.21 dB in Group-B ( < 0.049, statistically significant) whereas at 6 months, air conduction improved by 14.22% in Group-A ( < 0.01, statistically significant) and by 21.81% in Group-B ( < 0.001, highly statistically significant). Post-operatively at 3 months, improved AB gap was 62.5% in Group-A and 68.75% in Group-B patients. Post-operative AB gap at 6 months, improvement was seen in 78.12% in Group-A while it was 81.25% in Group-B patients. Alloplastic Teflon ossicle appears to be a good alternative for ossicular reconstruction where autologous incus is not available or disease precludes its use.

摘要

几乎任何形式的慢性化脓性中耳炎都可能破坏听骨链的完整性。各种材料已被用于听骨替代或重建,包括生物材料和异体材料。聚四氟乙烯活塞是目前在耳硬化症病例中重建听骨链最广泛使用的假体。耳科医生在手术操作以及特别是在社会经济地位较低和较差的人群中选择移植物类型方面,仍然面临听骨重建的问题。因此,人们感到有必要全面、整体地评估使用自体听小骨与异体听小骨(聚四氟乙烯)进行听骨成形术的结果。共有64例无活动性耳部感染且气骨导差超过15dB的慢性化脓性中耳炎患者入院接受手术,并根据听骨成形术所用材料分为A组(自体移植)和B组(异体移植)。术后3个月和6个月使用听力图对患者进行评估。在A组和B组中,术前平均气导分别为40.62dB(标准差9.65)和39.37(标准差10.53)。3个月时,A组从40.62dB变为37.03dB,变化了8.83%(P<0.109,无统计学意义),B组从39.37dB变为3,4.21dB,变化了13.10%(P<0.049,有统计学意义);而在6个月时,A组气导改善了14.22%(P<0.01,有统计学意义),B组改善了21.81%(P<0.001,高度有统计学意义)。术后3个月,A组患者改善的气骨导差为62.5%,B组为68.75%。术后6个月,A组气骨导差改善率为78.12%,B组为81.25%。在无法获得自体砧骨或疾病排除其使用的情况下,异体聚四氟乙烯听小骨似乎是听骨重建的一个很好的替代选择。