Mahajan Tamanna, Dass Arjun, Gupta Nitin, Chander Jagdish, Saini Vaibhav, Pol Shashikant A
1Department of ENT, Govt Medical College and Hospital, Sector-32, Chandigarh, India.
2Department of Microbiology, Govt Medical College and Hospital, Sector-32, Chandigarh, 160030 India.
Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 2):1412-1421. doi: 10.1007/s12070-018-1486-1. Epub 2018 Sep 4.
Chronic suppurative otitis media is defined as a chronic inflammation of the middle ear cleft, which presents with recurrent ear discharge through a tympanic membrane perforation. The purpose of this study was to find pattern of bacteriology in patients of atticoantral type of chronic suppurative otitis media as it will help the clinician to decide the effective antibiotics to be prescribed. This prospective and observational study was conducted in the Department of ENT in collaboration with Department of Microbiology, Government Medical College and Hospital, Chandigarh. The ear discharge specimen of all patients meeting the inclusion criteria were collected and sent for microbial examination. Culture positive samples were subjected to antibiotic sensitivity. A total of one hundred ears (mean age 27.33 years) clinically diagnosed with chronic suppurative otitis media, atticoantral type were included in this study based on the preset inclusion and exclusion. The male: female ratio in our patients was 0.94:1. Ninety-seven (96.9%) patients had unilateral disease, while 3 (3.1%) patients had bilateral disease. Twenty-eight percent of the total samples were sterile. The most common bacteria isolated were (27.1%), Methicillin sensitive (23.3%) and (6.5%). was sensitive to polymyxin B (100%) followed by ciprofloxacin (46.4%), neomycin (42.9%) and gentamicin (42.9%). Polymyxin B is the most effective antibiotic against the cultured bacteria followed by gentamicin, ciprofloxacin and neomycin.
慢性化脓性中耳炎被定义为中耳腔的慢性炎症,其表现为通过鼓膜穿孔反复出现耳漏。本研究的目的是找出上鼓室鼓窦型慢性化脓性中耳炎患者的细菌学模式,因为这将有助于临床医生决定开具有效的抗生素。这项前瞻性观察研究是在昌迪加尔政府医学院及医院的耳鼻喉科与微生物科合作下进行的。收集所有符合纳入标准患者的耳漏标本并送去进行微生物检查。培养阳性的样本进行抗生素敏感性检测。根据预先设定的纳入和排除标准,本研究共纳入了100只临床上诊断为上鼓室鼓窦型慢性化脓性中耳炎的耳朵(平均年龄27.33岁)。我们患者的男女比例为0.94:1。97名(96.9%)患者为单侧患病,而3名(3.1%)患者为双侧患病。总样本的28%无菌。分离出的最常见细菌是[未提及具体细菌名称1](27.1%)、甲氧西林敏感[未提及具体细菌名称2](23.3%)和[未提及具体细菌名称3](6.5%)。[未提及具体细菌名称1]对多粘菌素B敏感(100%),其次是环丙沙星(46.4%)、新霉素(42.9%)和庆大霉素(42.9%)。多粘菌素B是针对培养出的细菌最有效的抗生素,其次是庆大霉素、环丙沙星和新霉素。