Shilpa C, Sandeep S, Thanzeemunisa U, Prakash B G, Radhika S, Virender S
Department of ENT, JSS Medical College and hospital, Mahatma Gandhi Road, Mysuru, 570004 India.
Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 2):1449-1452. doi: 10.1007/s12070-018-1544-8. Epub 2018 Dec 3.
The aim of the study was to re- evaluate the current bacteriological profile of chronic suppurative otitis media and to know their antibiotic sensitivity pattern to commonly used antibiotics. To provide a guideline for empirical antibiotic therapy when culture facilities are not available. Observational study. Patients who presented to Ear, Nose and Throat department with chronic or recurrent ear discharge and on clinical examination found to have actively discharging ears were selected. Patients who did not receive antimicrobial therapy (topical or systemic) for the last 7 days were included. Out of the 106 ear swabs processed, bacterial growth was found in 100 samples (94.33%), while 6 samples (5.66%) showed no growth. The results revealed as the most isolated bacteria (49%), followed by (18%). Antibiotic susceptibility- was sensitive to Cefoperazone-Sulbactam (96%), Imipenem (82%), Piperacillin-Tazobactam (82%), Amikacin in 82% and Gentamicin (76%). It was found that Pseudomonas was sensitive to Ciprofloxacin in only 57% of the cases. isolates were sensitive to Vancomycin in 90%, Gentamicin in 81%, Clindamycin in 72%, and Erythromycin in 45%. It was found that 100% of the isolates were resistant to Ciprofloxacin. Our findings highlight the importance of continuous and periodic evaluation of microbiological pattern and antibiotic sensitivity of isolates in chronic suppurative otitis media patients to decrease the potential risk of complications by early institution of appropriate treatment.
本研究的目的是重新评估慢性化脓性中耳炎当前的细菌学特征,并了解其对常用抗生素的药敏模式。以便在没有培养设施时为经验性抗生素治疗提供指导。观察性研究。选择那些到耳鼻喉科就诊、有慢性或复发性耳漏且经临床检查发现耳朵有活动性流脓的患者。纳入最近7天未接受抗菌治疗(局部或全身)的患者。在处理的106份耳拭子中,100份样本(94.33%)发现有细菌生长,而6份样本(5.66%)未生长。结果显示,[细菌名称1]是最常见的分离菌(49%),其次是[细菌名称2](18%)。抗生素敏感性方面,[细菌名称1]对头孢哌酮-舒巴坦(96%)、亚胺培南(82%)、哌拉西林-他唑巴坦(82%)、阿米卡星(82%)和庆大霉素(76%)敏感。发现铜绿假单胞菌仅在57%的病例中对环丙沙星敏感。[细菌名称2]分离株对万古霉素的敏感率为90%,对庆大霉素为81%,对克林霉素为72%,对红霉素为45%。发现100%的分离株对环丙沙星耐药。我们的研究结果强调了持续和定期评估慢性化脓性中耳炎患者分离菌的微生物模式和抗生素敏感性的重要性,以便通过早期给予适当治疗降低并发症的潜在风险。