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单链聚合物纳米颗粒光触发合成的进展

Advances in the Phototriggered Synthesis of Single-Chain Polymer Nanoparticles.

作者信息

Verde-Sesto Ester, Blázquez-Martín Agustín, Pomposo José A

机构信息

Centro de Física de Materiales (CSIC, UPV/EHU) and Materials Physics Center MPC, Paseo Manuel de Lardizabal 5, E-20018 San Sebastián, Spain.

Departamento de Física de Materiales, Universidad del País Vasco (UPV/EHU), Apartado 1072, E-20800 San Sebastián, Spain.

出版信息

Polymers (Basel). 2019 Nov 18;11(11):1903. doi: 10.3390/polym11111903.

DOI:10.3390/polym11111903
PMID:31752235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6918210/
Abstract

Clean use of photons from light to activate chemical reactions offers many possibilities in different fields, from chemistry and biology to materials science and medicine. This review article describes the advances carried out in last decades toward the phototriggered synthesis of single-chain polymer nanoparticles (SCNPs) as soft nanomaterials with promising applications in enzyme-mimicking catalysis and nanomedicine, among other different uses. First, we summarize some different strategies developed to synthesize SCNPs based on photoactivated intrachain homocoupling, phototriggered intrachain heterocoupling and photogenerated collapse induced by an external cross-linker. Next, we comprehensively review the emergent topic of photoactivated multifolding applied to SCNP construction. Finally, we conclude by summarizing recent strategies towards phototriggered disassembly of SCNPs.

摘要

通过光的清洁光子利用来激活化学反应在从化学、生物学到材料科学和医学等不同领域提供了许多可能性。这篇综述文章描述了过去几十年在光触发合成单链聚合物纳米颗粒（SCNP）方面取得的进展，SCNP作为一种软纳米材料，在模拟酶催化和纳米医学等不同用途中具有广阔的应用前景。首先，我们总结了一些不同的策略，这些策略是基于光活化链内同偶联、光触发链内异偶联以及由外部交联剂诱导的光致塌陷来合成SCNP的。接下来，我们全面综述了应用于SCNP构建的光活化多折叠这一新兴主题。最后，我们通过总结近期关于光触发SCNP拆解的策略来得出结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/b156c74ae8a6/polymers-11-01903-g020.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/5be6b4f0bc8b/polymers-11-01903-sch001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/b156c74ae8a6/polymers-11-01903-g020.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/ed1479a04439/polymers-11-01903-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/5be6b4f0bc8b/polymers-11-01903-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/5362a1a05ffa/polymers-11-01903-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/2dcf56d9972b/polymers-11-01903-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/a97b52e8a171/polymers-11-01903-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/4a4c2fd15899/polymers-11-01903-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/79f343d525d9/polymers-11-01903-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/e097f6fa0bf8/polymers-11-01903-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/a268726bd986/polymers-11-01903-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/d2de0fb9bb72/polymers-11-01903-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/be928debd49b/polymers-11-01903-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/f415d02633d1/polymers-11-01903-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/515ed581a03f/polymers-11-01903-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/e00ab59b5c63/polymers-11-01903-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/a1be612cda4f/polymers-11-01903-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/1ff2ec004625/polymers-11-01903-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/2568ae0cebda/polymers-11-01903-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/52fff148ff97/polymers-11-01903-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23f3/6918210/b156c74ae8a6/polymers-11-01903-g020.jpg

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