基孔肯雅病毒的细胞附着和进入因子。
Cellular Attachment and Entry Factors for Chikungunya Virus.
机构信息
Department of Virology, Paul-Ehrlich-Institut, 63225 Langen, Germany.
出版信息
Viruses. 2019 Nov 19;11(11):1078. doi: 10.3390/v11111078.
Abstract
Chikungunya virus (CHIKV) is clinically the most relevant member of the genus. Like alphaviruses in general, CHIKV has the capacity to infect a large variety of cells, tissues, and species. This broad host tropism of CHIKV indicates that the virus uses a ubiquitously expressed receptor to infect cells. This review summarizes the current knowledge available on cellular CHIKV receptors and the attachment factors used by CHIKV.
摘要
基孔肯雅病毒（CHIKV）是该属中临床上最相关的成员。与一般的甲病毒一样，CHIKV 能够感染多种细胞、组织和物种。CHIKV 的这种广泛宿主趋向性表明该病毒使用普遍表达的受体感染细胞。这篇综述总结了目前关于细胞 CHIKV 受体和 CHIKV 使用的附着因子的知识。
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