浆细胞的栖息地：皮肤。
A Niche for Plasma Cells: The Skin.
机构信息
Department of Dermatology, Yale University, New Haven, Connecticut, USA.
Department of Dermatology, Yale University, New Haven, Connecticut, USA; Department of Pathology, Yale University, New Haven, Connecticut, USA.
出版信息
J Invest Dermatol. 2019 Dec;139(12):2411-2414. doi: 10.1016/j.jid.2019.06.133.
Antibodies are key components of the skin immune barrier, and antibodies directed toward skin structures can result in disease. Wilson et al. (2019) show that healthy skin is a niche for antibody secreting plasma cells and plasmablasts, and that inflammation and immunization increase their numbers. This work advances our understanding of skin associated B and plasma cells in health and disease.
抗体是皮肤免疫屏障的关键组成部分，针对皮肤结构的抗体可导致疾病。Wilson 等人（2019 年）表明，健康的皮肤是分泌抗体的浆细胞和浆母细胞的龛位，炎症和免疫接种会增加它们的数量。这项工作增进了我们对健康和疾病中皮肤相关 B 细胞和浆细胞的理解。
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