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子宫内膜异位症性卵巢囊肿不孕妇女的促排卵:现有证据和潜在陷阱。

Ovulation induction in infertile women with endometriotic ovarian cysts: current evidence and potential pitfalls.

机构信息

Department of Medicine, Nazarbayev University School of Medicine, Astana, Kazakhstan -

Clinical Academic Department of Women's Health, National Research Center of Mother and Child Health, University Medical Center, Astana, Kazakhstan -

出版信息

Minerva Med. 2020 Feb;111(1):50-61. doi: 10.23736/S0026-4806.19.06346-8. Epub 2019 Nov 12.

Abstract

Endometriosis is a chronic benign gynecological disease with symptoms that can severely impact quality of life and well-being. Women affected by endometriotic ovarian cyst could have associated infertility problems. Infertility affects 30% to 50% of women with endometriosis. Women with endometriosis are at risk of decreased ovarian reserve, due to the disease pathophysiologic mechanisms. Generally, infertility management include surgical procedure (usually with minimally invasive approach) and ovulation induction with intrauterine insemination or in vitro fertilization. Fertility preservation technologies also include oocyte or embryo freezing and ovarian tissue cryopreservation. Approach to patients with endometriotic cysts still remains controversial, and a multidisciplinary approach is a key factor to achieve the best outcome with appropriate patient counselling. Such management by a multidisciplinary team is a key factor in achieving the successful outcome.

摘要

子宫内膜异位症是一种慢性良性妇科疾病,其症状会严重影响生活质量和幸福感。患有子宫内膜异位症卵巢囊肿的女性可能会出现相关的不孕问题。30%至 50%的子宫内膜异位症女性受到不孕的影响。由于疾病的病理生理机制,子宫内膜异位症女性的卵巢储备功能会下降。一般来说,不孕的管理包括手术(通常采用微创方法)和排卵诱导,方法有宫腔内人工授精或体外受精。生育力保存技术还包括卵母细胞或胚胎冷冻和卵巢组织冷冻保存。针对子宫内膜异位症囊肿患者的治疗方法仍存在争议,多学科方法是实现最佳治疗效果和适当患者咨询的关键因素。多学科团队的这种管理是实现成功治疗效果的关键因素。

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