Gray Tara, Bassiri Nema, Kirby Neil, Stathakis Sotirios, Mayer Kathryn M
Department of Physics and Astronomy, The University of Texas at San Antonio, USA.
Department of Radiation Oncology, The University of Texas Health Science Center at San Antonio, USA.
Appl Radiat Isot. 2020 Jan;155:108925. doi: 10.1016/j.apradiso.2019.108925. Epub 2019 Nov 2.
Monte Carlo N-Particle 6 (MCNP6) is the latest version of Los Alamos National Laboratory's powerful Monte Carlo software designed to compute general photon, neutron, and electron transport using stochastic algorithms. Here we provide a case study of modeling the photon beam of a Varian 600C Clinical Linear Accelerator (linac), which is used to deliver radiation therapy, along with a comparison to experimentally measured beam characteristics. The source definition parameters in MCNP6, including the energy spectrum and angular spectrum of the photons, secondary and tertiary collimators, and a water phantom that tallied dose delivered at different points along the phantom are included. The experimental data for comparison was in the form of a percent depth dose curve as well as crossline and inline beam profiles. Experimental depth dose curve and beam profiles were acquired using a standard 0.125 cc ion chamber within a water phantom. In the computational model, the simulated depth dose curve was computed by tallying the total energy deposited in a stack of vertical slices down the depth of the phantom for percent depth dose curves. The simulated beam profiles were computed in a similar fashion, by tallying the energy deposited in a horizontal row, both in the x- and y-directions of cubic cells located at various depths. For the percent depth dose curve, a mean absolute percentage difference of 1.02%, 1.07%, and 1.94% were calculated for field sizes of 5 × 5 cm, 10 × 10 cm and 20 × 20 cm, respectively, between the model and experimental measurements were calculated. We present our model as an example to guide other MCNP6 users in the medical physics community to create similar beam models for biomedical dose estimation and research calculations for predicting dose to newly developed phantoms.
蒙特卡罗N粒子6(MCNP6)是洛斯阿拉莫斯国家实验室强大的蒙特卡罗软件的最新版本,旨在使用随机算法计算一般的光子、中子和电子输运。在此,我们提供了一个对瓦里安600C临床直线加速器(直线加速器)的光子束进行建模的案例研究,该直线加速器用于提供放射治疗,并与实验测量的束流特性进行比较。MCNP6中的源定义参数包括光子的能谱和角谱、二级和三级准直器,以及一个用于记录沿模体不同点处剂量的水体模。用于比较的实验数据采用百分深度剂量曲线以及交叉线和 inline 束流轮廓的形式。实验深度剂量曲线和束流轮廓是使用水体模内的标准0.125 cc离子室获取的。在计算模型中,通过记录沿模体深度向下的一叠垂直切片中沉积的总能量来计算模拟深度剂量曲线,以获得百分深度剂量曲线。模拟束流轮廓的计算方式类似,通过记录位于不同深度的立方体细胞在x和y方向的水平行中沉积的能量。对于百分深度剂量曲线,在模型与实验测量之间,计算得出5×5 cm、10×10 cm和20×20 cm射野尺寸的平均绝对百分比差异分别为1.