右心室功能能否预测慢性阻塞性肺疾病患者的生存率？
Does right ventricular function predict survival in patients with chronic obstructive lung disease?
作者信息
France A J, Prescott R J, Biernacki W, Muir A L, MacNee W
机构信息
Department of Respiratory Medicine, Rayne Laboratory, City Hospital, Edinburgh.
出版信息
Thorax. 1988 Aug;43(8):621-6. doi: 10.1136/thx.43.8.621.
Abstract
Non-invasive measurements of the right ventricular ejection fraction by radionuclide ventriculography were made in 115 patients with chronic obstructive lung disease. Survival was assessed over a mean period of 918 days. The right ventricular ejection fraction was reasonably normal in most patients (mean 0.42, range 0.10-0.66) but was lower in those with peripheral oedema, indicating cor pulmonale (mean 0.31 (SD 0.07); p less than 0.0001). Right ventricular ejection fraction was related to survival, but the relationship was weak (p = 0.03) by comparison with the association between the arterial oxygen and carbon dioxide tensions and survival (both p less than 0.0001). It is concluded that, although right ventricular function is predictive of survival in patients with chronic obstructive lung disease, it is probably a reflection of severity of disease and does not directly affect the prognosis.
摘要
对115例慢性阻塞性肺疾病患者进行了放射性核素心室造影术对右心室射血分数的无创测量。平均随访918天评估生存率。大多数患者的右心室射血分数基本正常（平均0.42，范围0.10 - 0.66），但有外周水肿提示肺心病的患者右心室射血分数较低（平均0.31（标准差0.07）；p<0.0001）。右心室射血分数与生存率相关，但与动脉血氧分压和二氧化碳分压与生存率之间的关联相比，这种关系较弱（p = 0.03）（两者p均<0.0001）。结论是，虽然右心室功能可预测慢性阻塞性肺疾病患者的生存率，但它可能只是疾病严重程度的反映，并不直接影响预后。
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Does right ventricular function predict survival in patients with chronic obstructive lung disease?右心室功能能否预测慢性阻塞性肺疾病患者的生存率？
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