School of Public Health and Management, Research Center for Medicine and Social Development, Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing 400016, China.
Global Health Research Center, Duke Kunshan University, Kunshan 215316, China.
Int J Environ Res Public Health. 2019 Jul 3;16(13):2348. doi: 10.3390/ijerph16132348.
: Hypertension is a major risk factor for cardiovascular diseases and stroke, and it requires lifelong medication. This study aimed to investigate the factors impacting on Health-Related Quality of Life (HRQoL) among hypertensive patients in Chongqing, China, and to provide evidence-based strategies to improve their HRQoL. : This cross-sectional survey was conducted in Chongqing, China. Of 600 randomly selected patients, 586 patients agreed to participate and 567 patients completed the survey. A SF-36 (Medical Outcomes Study (MOS) Short Form Health Survey questionnaire) that included eight domains: physical functioning, role limitations due to physical problems, body pain, general health, vitality, social function, role limitations due to emotional problems, and mental health was used to measure HRQoL. Linear regressions were used; each domain of HRQoL was measured in the stratification of sex. : Self-perceived relatively low economic burden caused by hypertension and regular physical activity had a positive impact on HRQoL ( < 0.05) for both men and women. For women, younger age was associated with higher scores of measuring physical functioning and body pain. Living with more than three family members had a positive impact on domains, including physical functioning. Emotional self-regulation had a positive association with women's mental health. Alcohol use for men was associated with higher scores in physical and mental health measures, and emotional self-regulation showed some positive impact on general health. : Perceived economic burden caused by hypertension was the most common factor impacting on patients' HRQoL. Female patients were more susceptible when compared to male patients. Health intervention strategies need to be further explored and adapted to the context of improving HRQoL for patients who suffer from hypertension and other chronic non-communicable diseases.
高血压是心血管疾病和中风的主要危险因素，需要终身服药。本研究旨在探讨中国重庆高血压患者健康相关生活质量（HRQoL）的影响因素，为提高其 HRQoL 提供循证策略。
本横断面调查在中国重庆进行。在随机选择的 600 名患者中，有 586 名患者同意参与，567 名患者完成了调查。采用 SF-36（医疗结局研究（MOS）短式健康调查问卷）评估 8 个领域的 HRQoL：身体机能、因身体问题导致的角色受限、身体疼痛、一般健康、活力、社会功能、因情绪问题导致的角色受限以及心理健康。采用线性回归；按性别分层测量 HRQoL 的每个领域。
自我感知的由高血压引起的相对较低的经济负担和有规律的体育锻炼对男女的 HRQoL 都有积极影响（<0.05）。对于女性，年龄较小与身体机能和身体疼痛的评分较高有关。与超过三个家庭成员一起生活对身体机能等领域有积极影响。情绪自我调节与女性的心理健康呈正相关。男性饮酒与身体和心理健康测量的得分较高有关，情绪自我调节对一般健康也有一定的积极影响。
由高血压引起的经济负担感知是影响患者 HRQoL 的最常见因素。与男性患者相比，女性患者更容易受到影响。需要进一步探讨和适应健康干预策略，以改善高血压和其他慢性非传染性疾病患者的 HRQoL。
