• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

辅助生殖技术中机器学习方法的综述

A Review of Machine Learning Approaches in Assisted Reproductive Technologies.

作者信息

Raef Behnaz, Ferdousi Reza

机构信息

Department of Health Information Technology, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran.

Department of Health Information Technology, Faculty of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Acta Inform Med. 2019 Sep;27(3):205-211. doi: 10.5455/aim.2019.27.205-211.

DOI:10.5455/aim.2019.27.205-211
PMID:31762579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6853715/
Abstract

INTRODUCTION

Assisted reproductive technologies (ART) are recent improvements in infertility treatment. However, there is no significant increase in pregnancy rates with the aid of ART. Costly and complex process of ART's makes them as challenging issues. Computational prediction models could predict treatment outcome, before the start of an ART cycle.

AIM

This review provides an overview on machine learning-based prediction models in ART.

METHODS

This article was executed based on a literature review through scientific databases search such as PubMed, Scopus, Web of Science and Google Scholar.

RESULTS

We identified 20 papers reporting on machine learning-based prediction models in IVF or ICSI settings. All of the models were validated only by internal validation. Therefore, external validation of the models and the impact analysis of them were the missing parts of the all studies.

CONCLUSION

Machine learning-based prediction models provide a clinical decision support tool for both clinicians and patients and lead to improvement in ART success rates.

摘要

引言

辅助生殖技术(ART)是不孕症治疗领域近期的进展。然而,借助ART并没有使妊娠率显著提高。ART成本高昂且过程复杂,这使其成为具有挑战性的问题。计算预测模型可以在ART周期开始前预测治疗结果。

目的

本综述概述了ART中基于机器学习的预测模型。

方法

本文通过在PubMed、Scopus、Web of Science和谷歌学术等科学数据库中进行文献检索来完成。

结果

我们确定了20篇报告体外受精(IVF)或卵胞浆内单精子注射(ICSI)环境下基于机器学习预测模型的论文。所有模型都仅通过内部验证进行了验证。因此,模型的外部验证及其影响分析是所有研究中缺失的部分。

结论

基于机器学习的预测模型为临床医生和患者提供了临床决策支持工具,并有助于提高ART成功率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e2/6853715/a25e3883eb4a/AIM-27-205-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e2/6853715/fc0231961447/AIM-27-205-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e2/6853715/a25e3883eb4a/AIM-27-205-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e2/6853715/fc0231961447/AIM-27-205-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e2/6853715/a25e3883eb4a/AIM-27-205-g002.jpg

相似文献

1
A Review of Machine Learning Approaches in Assisted Reproductive Technologies.辅助生殖技术中机器学习方法的综述
Acta Inform Med. 2019 Sep;27(3):205-211. doi: 10.5455/aim.2019.27.205-211.
2
In vitro fertilization and multiple pregnancies: an evidence-based analysis.体外受精与多胎妊娠:一项基于证据的分析。
Ont Health Technol Assess Ser. 2006;6(18):1-63. Epub 2006 Oct 1.
3
A Bayesian network model for prediction of low or failed fertilization in assisted reproductive technology based on a large clinical real-world data.基于大型临床真实世界数据的辅助生殖技术中低受精或受精失败预测的贝叶斯网络模型。
Reprod Biol Endocrinol. 2023 Jan 26;21(1):8. doi: 10.1186/s12958-023-01065-x.
4
International Committee for Monitoring Assisted Reproductive Technologies world report: assisted reproductive technology, 2014†.国际辅助生殖技术监测委员会世界报告:辅助生殖技术,2014 年†。
Hum Reprod. 2021 Oct 18;36(11):2921-2934. doi: 10.1093/humrep/deab198.
5
Prediction of pregnancy-related complications in women undergoing assisted reproduction, using machine learning methods.使用机器学习方法预测接受辅助生殖的女性的妊娠相关并发症。
Fertil Steril. 2024 Jul;122(1):95-105. doi: 10.1016/j.fertnstert.2024.02.024. Epub 2024 Feb 17.
6
Data-driven modeling and prediction of blood glucose dynamics: Machine learning applications in type 1 diabetes.基于数据驱动的血糖动力学建模与预测:机器学习在 1 型糖尿病中的应用。
Artif Intell Med. 2019 Jul;98:109-134. doi: 10.1016/j.artmed.2019.07.007. Epub 2019 Jul 26.
7
Economic evaluations of assisted reproductive technologies in high-income countries: a systematic review.高收入国家辅助生殖技术的经济评价:系统综述。
Hum Reprod. 2024 May 2;39(5):981-991. doi: 10.1093/humrep/deae039.
8
Derivation and validation of the first web-based nomogram to predict the spontaneous pregnancy after reproductive surgery using machine learning models.首个基于网络的列线图的推导与验证,该列线图利用机器学习模型预测生殖手术后的自然妊娠情况。
Front Endocrinol (Lausanne). 2024 Jul 2;15:1378157. doi: 10.3389/fendo.2024.1378157. eCollection 2024.
9
The vaginal microbiome as a predictor for outcome of in vitro fertilization with or without intracytoplasmic sperm injection: a prospective study.阴道微生物组作为体外受精(无论是否进行胞浆内单精子注射)结局的预测因素:一项前瞻性研究。
Hum Reprod. 2019 Jun 4;34(6):1042-1054. doi: 10.1093/humrep/dez065.
10
International Committee for Monitoring Assisted Reproductive Technologies world report: assisted reproductive technology 2012†.国际辅助生殖技术监测委员会世界报告:辅助生殖技术 2012 年报告†。
Hum Reprod. 2020 Aug 1;35(8):1900-1913. doi: 10.1093/humrep/deaa090.

引用本文的文献

1
Semen HPV and IVF: insights from infection prevalence to embryologic outcomes.精液中的人乳头瘤病毒与体外受精:从感染率到胚胎学结局的见解
J Assist Reprod Genet. 2025 May 22. doi: 10.1007/s10815-025-03513-6.
2
Visual interpretability of image-based classification models by generative latent space disentanglement applied to in vitro fertilization.基于生成潜在空间解缠的体外受精图像分类模型的可视化可解释性。
Nat Commun. 2024 Aug 27;15(1):7390. doi: 10.1038/s41467-024-51136-9.
3
Factors affecting biochemical pregnancy loss (BPL) in preimplantation genetic testing for aneuploidy (PGT-A) cycles: machine learning-assisted identification.

本文引用的文献

1
Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization.深度学习有助于在体外受精后对人类囊胚进行可靠的评估和筛选。
NPJ Digit Med. 2019 Apr 4;2:21. doi: 10.1038/s41746-019-0096-y. eCollection 2019.
2
Prediction of implantation after blastocyst transfer in in vitro fertilization: a machine-learning perspective.体外受精中囊胚移植后着床的预测:机器学习视角。
Fertil Steril. 2019 Feb;111(2):318-326. doi: 10.1016/j.fertnstert.2018.10.030. Epub 2019 Jan 2.
3
Predicting Implantation Outcome of In Vitro Fertilization and Intracytoplasmic Sperm Injection Using Data Mining Techniques.
影响植入前非整倍体基因检测(PGT-A)周期中生化妊娠丢失(BPL)的因素:机器学习辅助识别
Reprod Biol Endocrinol. 2024 Aug 8;22(1):101. doi: 10.1186/s12958-024-01271-1.
4
A novel machine-learning framework based on early embryo morphokinetics identifies a feature signature associated with blastocyst development.一种基于早期胚胎形态动力学的新型机器学习框架,确定了与囊胚发育相关的特征特征。
J Ovarian Res. 2024 Mar 15;17(1):63. doi: 10.1186/s13048-024-01376-6.
5
A hybrid feature selection algorithm to determine effective factors in predictive model of success rate for in vitro fertilization/intracytoplasmic sperm injection treatment: A cross-sectional study.一种用于确定体外受精/卵胞浆内单精子注射治疗成功率预测模型中有效因素的混合特征选择算法:一项横断面研究。
Int J Reprod Biomed. 2024 Jan 25;21(12):995-1012. doi: 10.18502/ijrm.v21i12.15038. eCollection 2023 Dec.
6
Using feature optimization and LightGBM algorithm to predict the clinical pregnancy outcomes after fertilization.使用特征优化和 LightGBM 算法预测受精后的临床妊娠结局。
Front Endocrinol (Lausanne). 2023 Nov 29;14:1305473. doi: 10.3389/fendo.2023.1305473. eCollection 2023.
7
Using Unlabeled Information of Embryo Siblings from the Same Cohort Cycle to Enhance In Vitro Fertilization Implantation Prediction.利用同一队列周期中胚胎同胞的未标记信息来提高体外受精的胚胎种植预测。
Adv Sci (Weinh). 2023 Sep;10(27):e2207711. doi: 10.1002/advs.202207711. Epub 2023 Jul 28.
8
Multi-omics and machine learning for the prevention and management of female reproductive health.多组学和机器学习在女性生殖健康的预防和管理中的应用。
Front Endocrinol (Lausanne). 2023 Feb 23;14:1081667. doi: 10.3389/fendo.2023.1081667. eCollection 2023.
9
Artificial Intelligence in Reproductive Medicine - An Ethical Perspective.生殖医学中的人工智能——伦理视角
Geburtshilfe Frauenheilkd. 2023 Jan 11;83(1):106-115. doi: 10.1055/a-1866-2792. eCollection 2023 Jan.
10
Application of machine learning to predict aneuploidy and mosaicism in embryos from in vitro fertilization cycles.机器学习在预测体外受精周期胚胎非整倍体和嵌合体中的应用。
AJOG Glob Rep. 2022 Sep 19;2(4):100103. doi: 10.1016/j.xagr.2022.100103. eCollection 2022 Nov.
使用数据挖掘技术预测体外受精和卵胞浆内单精子注射的着床结局
Int J Fertil Steril. 2017 Oct;11(3):184-190. doi: 10.22074/ijfs.2017.4882. Epub 2017 Aug 27.
4
The International Glossary on Infertility and Fertility Care, 2017.《国际不孕不育和生育保健词汇表》,2017 年。
Fertil Steril. 2017 Sep;108(3):393-406. doi: 10.1016/j.fertnstert.2017.06.005. Epub 2017 Jul 29.
5
Performing the embryo transfer: a guideline.胚胎移植操作指南
Fertil Steril. 2017 Apr;107(4):882-896. doi: 10.1016/j.fertnstert.2017.01.025.
6
Applying data mining techniques for increasing implantation rate by selecting best sperms for intra-cytoplasmic sperm injection treatment.应用数据挖掘技术,通过为胞浆内单精子注射治疗选择最佳精子来提高着床率。
Comput Methods Programs Biomed. 2016 Dec;137:215-229. doi: 10.1016/j.cmpb.2016.09.013. Epub 2016 Sep 26.
7
Predicting the chances of a live birth after one or more complete cycles of in vitro fertilisation: population based study of linked cycle data from 113 873 women.预测经过一个或多个完整体外受精周期后活产的几率:基于113873名女性相关周期数据的人群研究
BMJ. 2016 Nov 16;355:i5735. doi: 10.1136/bmj.i5735.
8
Selecting the embryo with the highest implantation potential using a data mining based prediction model.使用基于数据挖掘的预测模型选择具有最高着床潜力的胚胎。
Reprod Biol Endocrinol. 2016 Mar 3;14:10. doi: 10.1186/s12958-016-0145-1.
9
Machine Learning in Medicine.医学中的机器学习
Circulation. 2015 Nov 17;132(20):1920-30. doi: 10.1161/CIRCULATIONAHA.115.001593.
10
Predicting the chance of live birth for women undergoing IVF: a novel pretreatment counselling tool.预测接受体外受精的女性的活产几率:一种新型的预处理咨询工具。
Hum Reprod. 2016 Jan;31(1):84-92. doi: 10.1093/humrep/dev268. Epub 2015 Oct 25.