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慢性钙化性胰腺炎合并胆管炎和胆管狭窄的胆道片形吸虫病

Biliary Fascioliasis in Chronic Calcific Pancreatitis Presenting with Ascending Cholangitis and Biliary Stricture.

作者信息

Pattarapuntakul Tanawat, Ovartlarnporn Bancha, Rojsanga Worapot, Yungyoo Thanaidpon

机构信息

NKC Institute of Gastroenterology and Hepatology, Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.

Internal Medicine, Shanghai Medical College, Fudan University, Shanghai, China.

出版信息

Case Rep Gastroenterol. 2019 Oct 9;13(3):438-444. doi: 10.1159/000503277. eCollection 2019 Sep-Dec.

Abstract

Biliary fascioliasis is a rare infection of the hepatobiliary system. In human, it is known to present with two main phases; acute phase (hepatic phase) presenting with abdominal pain or abnormal liver biochemistry then chronic phase (biliary phase) presenting with biliary obstruction or cholangitis. Optimal treatment of biliary fascioliasis consists of endoscopic retrograde cholangiography with removal of the parasite and single oral dose of triclabendazole. We report a rare case of biliary fascioliasis in chronic calcified pancreatitis who presented with ascending cholangitis and biliary stricture. A 63-years-old Thai man was referred to our hospital for treatment of clinical symptoms severe cholangitis. Magnetic resonance cholangiopancreatography showed evidence of distal common bile duct stricture associated with chronic calcific pancreatitis. ERCP was performed, that found a few amorphous filling defects in the common bile duct and distal biliary stricture. After removal of the foreign body of what seems to be a fluke parasite followed with single oral dose triclabendazole thereafter, the clinical symptom was improved dramatically.

摘要

胆管片形吸虫病是一种罕见的肝胆系统感染。在人类中,已知其有两个主要阶段:急性期(肝脏期)表现为腹痛或肝脏生化指标异常,然后是慢性期(胆管期)表现为胆管梗阻或胆管炎。胆管片形吸虫病的最佳治疗方法包括内镜逆行胆管造影术以清除寄生虫,并单次口服三氯苯达唑。我们报告了一例罕见的慢性钙化性胰腺炎合并胆管片形吸虫病病例,该患者表现为化脓性胆管炎和胆管狭窄。一名63岁的泰国男子因严重胆管炎的临床症状被转诊至我院治疗。磁共振胰胆管造影显示存在与慢性钙化性胰腺炎相关的胆总管远端狭窄。进行了内镜逆行胰胆管造影术,发现胆总管内有一些无定形充盈缺损和远端胆管狭窄。在取出似乎是吸虫寄生虫的异物并随后单次口服三氯苯达唑后,临床症状显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/872c/6873016/afa91589f2bf/crg-0013-0438-g01.jpg

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