Kuttab Hani I, Harris Elizabeth A, Tataris Katie L, Tao James, Beiser David G
University of Chicago Medical Center, Section of Emergency Medicine, Chicago, Illinois.
Clin Pract Cases Emerg Med. 2019 Aug 5;3(4):354-356. doi: 10.5811/cpcem.2019.6.43173. eCollection 2019 Nov.
Sudden unexplained death in epilepsy (SUDEP) refers to a death in a patient with epilepsy that is not due to trauma, drowning, status epilepticus, or another apparent cause. Although the pathophysiology of SUDEP is incompletely understood, growing evidence supports the role of seizure-associated arrhythmias as a potential etiology. We present a unique case of a patient presenting with ventricular tachycardia shortly following a seizure, along with corresponding laboratory data. Awareness of high risk arrhythmias in seizure patients could lead to advances in understanding pathophysiology and treatment of this complication of seizure disorder and ultimately prevention of SUDEP.
癫痫性猝死（SUDEP）是指癫痫患者发生的并非由外伤、溺水、癫痫持续状态或其他明显原因导致的死亡。尽管SUDEP的病理生理学尚未完全明了，但越来越多的证据支持癫痫发作相关心律失常作为一种潜在病因所起的作用。我们报告了一例独特病例，患者在癫痫发作后不久出现室性心动过速，并给出了相应的实验室数据。认识到癫痫发作患者中的高危心律失常可能会推动对癫痫发作障碍这一并发症的病理生理学及治疗的理解取得进展，并最终预防SUDEP。
