Pryjma J, Strzyzewska J, Pryjma K
Arch Immunol Ther Exp (Warsz). 1979;27(5):621-7.
Spleen and bone marrow cells depleted of CRL cannot restore immune reactivity of irradiated mice to sheep red blood cells SRBC. The response to anti-SIII, a T-independent antigen does not change when irradiated animals are repopulated with spleen cells or spleen cells depleted of CRL. Spleen cells of 6-day-old mice having low number of CRL, in contrast to spleen cells of adult animals, could not reconstitute irradiated recipients.
去除CRL的脾细胞和骨髓细胞无法恢复受辐照小鼠对绵羊红细胞(SRBC)的免疫反应性。当用脾细胞或去除CRL的脾细胞对受辐照动物进行再移植时,对非T细胞依赖性抗原抗SIII的反应不会改变。与成年动物的脾细胞相比,6日龄小鼠的脾细胞中CRL数量较少,无法重建受辐照的受体。