基于pH敏感共价动态超支化聚合物的纳米晶体封装、释放及应用

Nanocrystal Encapsulation, Release and Application Based on pH-Sensitive Covalent Dynamic Hyperbranched Polymers.

作者信息

Shi Yunfeng, Lei Gaiying, Zhou Linzhu, Li Yueyang, Zhang Xiaoming, Yang Yujiao, Peng Han, Peng Rui, Wang Huichun, Cai Xiufen, Chen Xinglong, Wang Mengyue, Wang Gang

机构信息

School of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.

Henan Province Key Laboratory of New Optoelectronic Functional Materials, Anyang Normal University, Anyang 455000, China.

出版信息

Polymers (Basel). 2019 Nov 22;11(12):1926. doi: 10.3390/polym11121926.

DOI:10.3390/polym11121926

PMID:31766705

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6960846/

Abstract

A new strategy for nanocrystal encapsulation, release and application based on pH-sensitive covalent dynamic hyperbranched polymers is described. The covalent dynamic hyperbranched polymers, with multi-arm hydrophobic chains and a hydrophilic hyperbranched poly(amidoamine) (HPAMAM) core connected with pH-sensitive imine bonds (HPAMAM-DA), could encapsulate CdTe quantum dots (QDs) and Au nanoparticles (NPs). Benefiting from its pH response property, CdTe QDs and Au NPs encapsulated by HPAMAM-DA could be released to aqueous phase after imine hydrolysis. The released CdTe/HPAMAM and Au/HPAMAM nanocomposites exhibited excellent biological imaging behavior and high catalytic activities on -nitrophenol hydrogenation, respectively.

摘要

本文描述了一种基于pH敏感的共价动态超支化聚合物的纳米晶体封装、释放及应用的新策略。共价动态超支化聚合物具有多臂疏水链和通过pH敏感的亚胺键连接的亲水性超支化聚（酰胺胺）（HPAMAM）核（HPAMAM-DA），能够封装碲化镉量子点（QDs）和金纳米颗粒（NPs）。得益于其pH响应特性，被HPAMAM-DA封装的碲化镉量子点和金纳米颗粒在亚胺水解后可释放到水相中。释放出的CdTe/HPAMAM和Au/HPAMAM纳米复合材料分别表现出优异的生物成像行为和对硝基苯酚氢化的高催化活性。