Department of Pediatrics, Alvaro Cunqueiro Hospital, Vigo, Spain.
Department of Neonatology, Alvaro Cunqueiro Hospital, Vigo, Spain.
J Perinatol. 2020 Feb;40(2):226-231. doi: 10.1038/s41372-019-0557-9. Epub 2019 Nov 25.
Determine the suitability of transcutaneous bilirubin (TCB) as a tool to assess the effectiveness of phototherapy on patched skin.
A prospective observational study was conducted. We covered a fragment of skin (sternum) with a photo-opaque patch. Several simultaneous TCB and TSB measurements were performed with the JM-105 bilirubinometer. Bland and Altman test evaluated the agreement between bilirubin levels.
A total of 217 patients were studied, 48.8% were preterm. The mean difference between TSB and TCB before the start of treatment was 1.07 mg/dL. During phototherapy, differences on covered skin were 0.52, 0.27, and 0.39 mg/dL at 24, 48, and 72 h of therapy respectively. The best correlation was observed at 48 h in preterm infants.
The measurement of TCB on patched skin (PTCB) is useful for monitoring the response to phototherapy in term and preterm infants. We use a patch with a removable flap that eases successive measures without disturbing the patients.
确定经皮胆红素（TCB）作为评估光疗对贴皮效果的工具的适用性。
进行了一项前瞻性观察性研究。我们用不透光贴片覆盖皮肤的一小部分（胸骨）。使用 JM-105 胆红素计同时进行多次 TCB 和 TSB 测量。Bland-Altman 检验评估胆红素水平的一致性。
共研究了 217 例患者，其中 48.8%为早产儿。治疗开始前 TSB 和 TCB 之间的平均差值为 1.07mg/dL。在光疗期间，治疗 24、48 和 72 小时时贴皮部位的差异分别为 0.52、0.27 和 0.39mg/dL。早产儿在 48 小时时观察到最佳相关性。
测量贴皮 TCB（PTCB）可用于监测足月和早产儿对光疗的反应。我们使用带有可移动皮瓣的贴片，便于在不干扰患者的情况下进行连续测量。
