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Tipping the scales: Are females more at risk for obesity- and high-fat diet-induced hypertension and vascular dysfunction?打破平衡:女性更容易患肥胖症和高脂肪饮食引起的高血压和血管功能障碍吗?
Br J Pharmacol. 2019 Nov;176(21):4226-4242. doi: 10.1111/bph.14783. Epub 2019 Aug 19.
2
Sex differences in the hypothalamic-pituitary-adrenal axis: An obstacle to antidepressant drug development?下丘脑-垂体-肾上腺轴的性别差异:抗抑郁药物研发的障碍?
Br J Pharmacol. 2019 Nov;176(21):4090-4106. doi: 10.1111/bph.14710. Epub 2019 Jun 26.
3
Sex as a biological variable in the pathology and pharmacology of neurodegenerative and neurovascular diseases.性别作为神经退行性和神经血管疾病病理和药理学的生物学变量。
Br J Pharmacol. 2019 Nov;176(21):4173-4192. doi: 10.1111/bph.14675. Epub 2019 May 21.
4
Discovery of early life stress interacting and sex-specific quantitative trait loci impacting cocaine responsiveness.发现早期生活应激与性别特异性数量性状基因座相互作用,影响可卡因反应性。
Br J Pharmacol. 2019 Nov;176(21):4159-4172. doi: 10.1111/bph.14661. Epub 2019 May 11.
5
Metabolic control and sex: A focus on inflammatory-linked mediators.代谢控制与性别:关注炎症相关介质。
Br J Pharmacol. 2019 Nov;176(21):4193-4207. doi: 10.1111/bph.14642. Epub 2019 Apr 21.
6
Sex differences in mechanisms of arterial stiffness.动脉僵硬度机制的性别差异。
Br J Pharmacol. 2019 Nov;176(21):4208-4225. doi: 10.1111/bph.14624. Epub 2019 May 11.
7
Sex differences in mouse models of fear inhibition: Fear extinction, safety learning, and fear-safety discrimination.小鼠恐惧抑制模型中的性别差异:恐惧消退、安全学习和恐惧-安全辨别。
Br J Pharmacol. 2019 Nov;176(21):4149-4158. doi: 10.1111/bph.14600. Epub 2019 Apr 15.
8
Sex differences in schizophrenia, bipolar disorder, and post-traumatic stress disorder: Are gonadal hormones the link?精神分裂症、双相情感障碍和创伤后应激障碍中的性别差异:性腺激素是其中的联系吗?
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9
Sex bias in preclinical research and an exploration of how to change the status quo.临床前研究中的性别偏见及改变现状的探索
Br J Pharmacol. 2019 Nov;176(21):4107-4118. doi: 10.1111/bph.14539. Epub 2018 Dec 12.
10
Oestradiol influences on dopamine release from the nucleus accumbens shell: sex differences and the role of selective oestradiol receptor subtypes.雌激素对壳核多巴胺释放的影响:性别差异和选择性雌激素受体亚型的作用。
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药理学研究中性别差异的重要性。

The importance of sex differences in pharmacology research.

机构信息

Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.

Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.

出版信息

Br J Pharmacol. 2019 Nov;176(21):4087-4089. doi: 10.1111/bph.14819.

DOI:10.1111/bph.14819
PMID:31769019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6877793/
Abstract

This article is part of a themed section on The Importance of Sex Differences in Pharmacology Research. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.21/issuetoc.

摘要

这篇文章是药理学研究中性别差异重要性专题的一部分。要查看本部分中的其他文章,请访问 http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.21/issuetoc.