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子宫内膜基质细胞中类固醇受体水平与催乳素水平之间的关系。

Relation between steroid receptor levels and prolactin level in the endometrial stromal cells.

作者信息

Tamaya T, Arabori K, Okada H

机构信息

Department of Obstetrics and Gynecology, Gifu University School of Medicine, Japan.

出版信息

Acta Obstet Gynecol Scand. 1988;67(3):265-9. doi: 10.3109/00016348809004217.

DOI:10.3109/00016348809004217
PMID:3176947
Abstract

The levels of estrogen receptors (ERs), progesterone receptors (PRs), androgen receptors (ARs) and prolactin (PRL) in the stromal cells were determined during the secretory phase of the endometrium. The total levels of cellular ER during the early and mid-secretory phases and those in cellular PR during the mid-secretory phase were significantly higher than those during the late secretory phase. No changes were seen in stromal AR level during these phases. The total ER levels was always significantly higher than those of other receptors in any phase of endometrium. The total AR level was significantly higher than the PR level in any phase of endometrium except that in late secretory phase. Cytosol PRL levels were low in 42% of the subjects in whom PRL was detected. The cytosol PRL level in these subjects was inversely correlated only to cellular ER levels.

摘要

在子宫内膜分泌期测定基质细胞中雌激素受体(ERs)、孕激素受体(PRs)、雄激素受体(ARs)和催乳素(PRL)的水平。分泌早期和中期的细胞ER总水平以及分泌中期的细胞PR总水平显著高于分泌晚期。在这些阶段,基质AR水平未见变化。在子宫内膜的任何阶段,ER总水平始终显著高于其他受体。除分泌晚期外,在子宫内膜的任何阶段,AR总水平均显著高于PR水平。在检测到PRL的受试者中,42%的受试者胞质PRL水平较低。这些受试者的胞质PRL水平仅与细胞ER水平呈负相关。

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