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肝肺综合征中的平卧呼吸和直立性低氧血症

Platypnoea and orthodeoxia in the hepatopulmonary syndrome.

作者信息

Surridge Anna, Atkinson Jane, Aujayeb Avinash

机构信息

Acute Medicine Department, Northumbria Healthcare NHS Foundation Trust, Newcastle Upon Tyne, UK.

Acute Medicine Department, Northumbria Healthcare NHS Foundation Trust, Newcastle Upon Tyne, UK

出版信息

BMJ Case Rep. 2019 Nov 26;12(11):e231499. doi: 10.1136/bcr-2019-231499.

DOI:10.1136/bcr-2019-231499
PMID:31776152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6887442/
Abstract

A 71-year-old female patient with alcohol-induced cirrhosis presented with symptoms of dyspnoea. Previous extensive investigations had detected no apparent cause. Platypnoea and orthodeoxia were observed. A bubble echocardiogram revealed significant intracardiac shunting and a diagnosis of hepatopulmonary syndrome was made. The patient was discharged on home oxygen and referred for liver transplantation.

摘要

一名71岁酒精性肝硬化女性患者出现呼吸困难症状。此前的广泛检查未发现明显病因。观察到平卧呼吸和直立性低氧血症。气泡超声心动图显示显著的心内分流，诊断为肝肺综合征。患者出院时携带家庭用氧，并被转诊进行肝移植。

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本文引用的文献

1
Platypnea-orthodeoxia Syndrome in a Patient with Cryptogenic Liver Cirrhosis: An Elusive Cause of Hypoxemia.隐源性肝硬化患者的平卧呼吸困难-直立性低氧血症综合征：一种难以捉摸的低氧血症原因。
Cureus. 2019 Jan 8;11(1):e3846. doi: 10.7759/cureus.3846.
2
The multiple dimensions of Platypnea-Orthodeoxia syndrome: A review.平卧呼吸-直立性低氧血症综合征的多维度研究：综述
Respir Med. 2017 Aug;129:31-38. doi: 10.1016/j.rmed.2017.05.016. Epub 2017 May 31.
3
Clinical characteristics, predictors, and survival among patients with hepatopulmonary syndrome.肝肺综合征患者的临床特征、预测因素及生存率
Ann Hepatol. 2015 May-Jun;14(3):354-60.
4
Current concepts in the management of hepatopulmonary syndrome.肝肺综合征管理的当前概念
Vasc Health Risk Manag. 2008;4(5):1035-41. doi: 10.2147/vhrm.s3608.
5
Hepatopulmonary syndrome--a liver-induced lung vascular disorder.肝肺综合征——一种由肝脏引起的肺血管疾病。
N Engl J Med. 2008 May 29;358(22):2378-87. doi: 10.1056/NEJMra0707185.
6
Gas exchange mechanism of orthodeoxia in hepatopulmonary syndrome.肝肺综合征中正位低氧血症的气体交换机制
Hepatology. 2004 Sep;40(3):660-6. doi: 10.1002/hep.20358.

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