• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Bites by the Philippine cobra (Naja naja philippinensis): prominent neurotoxicity with minimal local signs.

作者信息

Watt G, Padre L, Tuazon L, Theakston R D, Laughlin L

机构信息

U.S. Naval Medical Research Unit No. 2, APO San Francisco, California 96528.

出版信息

Am J Trop Med Hyg. 1988 Sep;39(3):306-11. doi: 10.4269/ajtmh.1988.39.306.

DOI:10.4269/ajtmh.1988.39.306
PMID:3177741
Abstract

We studied 39 patients envenomed by the Philippine cobra (Naja naja philippinensis). Neurotoxicity occurred in 38 cases and was the predominant clinical feature. Respiratory paralysis developed in 19 patients, and was often rapid in onset--in 3 cases apnea occurred within 30 min of the bite. There were 2 deaths, both in patients who were moribund upon arrival at the hospital. Three patients developed necrosis, and 14 individuals with systemic symptoms had no local swelling. Both cardiotoxicity and reliable nonspecific signs of envenoming were absent. Bites by the Philippine cobra produce a distinctive clinical picture characterized by severe neurotoxicity of rapid onset and minimal local tissue damage.

摘要

相似文献

1
Bites by the Philippine cobra (Naja naja philippinensis): prominent neurotoxicity with minimal local signs.
Am J Trop Med Hyg. 1988 Sep;39(3):306-11. doi: 10.4269/ajtmh.1988.39.306.
2
Tourniquet application after cobra bite: delay in the onset of neurotoxicity and the dangers of sudden release.眼镜蛇咬伤后使用止血带:神经毒性发作延迟及突然松开的危险
Am J Trop Med Hyg. 1988 May;38(3):618-22. doi: 10.4269/ajtmh.1988.38.618.
3
Bites by the Philippine cobra (Naja naja philippinensis): an important cause of death among rice farmers.
Am J Trop Med Hyg. 1987 Nov;37(3):636-9. doi: 10.4269/ajtmh.1987.37.636.
4
Proteomic insights into short neurotoxin-driven, highly neurotoxic venom of Philippine cobra (Naja philippinensis) and toxicity correlation of cobra envenomation in Asia.蛋白质组学揭示菲律宾眼镜蛇(Naja philippinensis)短神经毒素驱动的高度神经毒性毒液的特性及亚洲眼镜蛇咬伤的毒性相关性。
J Proteomics. 2019 Aug 30;206:103418. doi: 10.1016/j.jprot.2019.103418. Epub 2019 Jun 12.
5
Epidemiology, clinical profile and management issues of cobra (Naja naja) bites in Sri Lanka: first authenticated case series.斯里兰卡眼镜蛇(Naja naja)咬伤的流行病学、临床特征和处理问题:首例经证实的病例系列。
Trans R Soc Trop Med Hyg. 2009 Sep;103(9):924-30. doi: 10.1016/j.trstmh.2009.04.002. Epub 2009 May 12.
6
Envenoming by the common krait (Bungarus caeruleus) and Sri Lankan cobra (Naja naja naja): efficacy and complications of therapy with Haffkine antivenom.普通眼镜蛇(孟加拉眼镜蛇)和斯里兰卡眼镜蛇(眼镜蛇指名亚种)咬伤:哈夫金抗蛇毒血清治疗的疗效及并发症
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):301-8. doi: 10.1016/0035-9203(90)90297-r.
7
Development of a Treatment Protocol for Cobra () Bite Envenoming in Dogs.制定犬类眼镜蛇咬伤治疗方案。
Toxins (Basel). 2020 Nov 2;12(11):694. doi: 10.3390/toxins12110694.
8
Snake bites by the Papuan taipan (Oxyuranus scutellatus canni): paralysis, hemostatic and electrocardiographic abnormalities, and effects of antivenom.巴布亚太攀蛇(Oxyuranus scutellatus canni)咬伤:麻痹、止血及心电图异常,以及抗蛇毒血清的作用
Am J Trop Med Hyg. 1995 Jun;52(6):525-31. doi: 10.4269/ajtmh.1995.52.525.
9
Clinical features of neurotoxic snake bite and response to antivenom in 47 children.47例儿童神经毒性蛇咬伤的临床特征及抗蛇毒血清反应
Am J Trop Med Hyg. 1984 Nov;33(6):1258-66. doi: 10.4269/ajtmh.1984.33.1258.
10
Comparison of Tensilon and antivenom for the treatment of cobra-bite paralysis.
Trans R Soc Trop Med Hyg. 1989 Jul-Aug;83(4):570-3. doi: 10.1016/0035-9203(89)90301-5.

引用本文的文献

1
Cytotoxicity of Venoms and Cytotoxins from Asiatic Cobras (, , ) and Neutralization by Antivenoms from Thailand, Vietnam, and Taiwan.亚洲眼镜蛇(、、)毒液和细胞毒素的细胞毒性及来自泰国、越南和中国台湾地区抗蛇毒血清的中和作用。
Toxins (Basel). 2022 May 10;14(5):334. doi: 10.3390/toxins14050334.
2
Snake Venomics: Fundamentals, Recent Updates, and a Look to the Next Decade.蛇毒组学:基础、最新进展和未来十年展望。
Toxins (Basel). 2022 Mar 30;14(4):247. doi: 10.3390/toxins14040247.
3
Snake Venom Proteomics of Samar Cobra (Naja samarensis) from the Southern Philippines: Short Alpha-Neurotoxins as the Dominant Lethal Component Weakly Cross-Neutralized by the Philippine Cobra Antivenom.
菲律宾南部萨马尔眼镜蛇(Naja samarensis)的蛇毒蛋白质组学:短α-神经毒素作为主要致死成分,被菲律宾眼镜蛇抗蛇毒血清微弱交叉中和。
Front Pharmacol. 2021 Dec 24;12:727756. doi: 10.3389/fphar.2021.727756. eCollection 2021.
4
Managing snakebite.处理蛇咬伤
BMJ. 2022 Jan 7;376:e057926. doi: 10.1136/bmj-2020-057926.
5
Influential Factors of Local Tissue Necrosis after Taiwan Cobra Bites: A Secondary Analysis of the Clinical Significance of Venom Detection in Patients of Cobra Snakebites.台湾眼镜蛇咬伤后局部组织坏死的影响因素:毒蛇咬伤患者毒液检测临床意义的二次分析。
Toxins (Basel). 2021 May 7;13(5):338. doi: 10.3390/toxins13050338.
6
Convergent evolution of pain-inducing defensive venom components in spitting cobras.吐舌眼镜蛇致痛防御性毒液成分的趋同进化。
Science. 2021 Jan 22;371(6527):386-390. doi: 10.1126/science.abb9303.
7
An agonist of the CXCR4 receptor accelerates the recovery from the peripheral neuroparalysis induced by Taipan snake envenomation.CXCR4 受体激动剂加速了太攀蛇毒液中毒引起的周围神经麻痹的恢复。
PLoS Negl Trop Dis. 2020 Sep 8;14(9):e0008547. doi: 10.1371/journal.pntd.0008547. eCollection 2020 Sep.
8
The Urgent Need to Develop Novel Strategies for the Diagnosis and Treatment of Snakebites.迫切需要开发新的策略来诊断和治疗蛇咬伤。
Toxins (Basel). 2019 Jun 20;11(6):363. doi: 10.3390/toxins11060363.
9
Antivenom for Neuromuscular Paralysis Resulting From Snake Envenoming.治疗蛇咬伤所致神经肌肉麻痹的抗蛇毒血清。
Toxins (Basel). 2017 Apr 19;9(4):143. doi: 10.3390/toxins9040143.
10
Neurotoxicity in snakebite--the limits of our knowledge.蛇伤中毒性神经病变——我们认识的局限性。
PLoS Negl Trop Dis. 2013 Oct 10;7(10):e2302. doi: 10.1371/journal.pntd.0002302. eCollection 2013.