Division of Gastroenterology, Humanitas Research Hospital, Digestive Endoscopy Unit, Rozzano, Italy.
Expert Rev Med Devices. 2019 Dec;16(12):1053-1061. doi: 10.1080/17434440.2019.1697229. Epub 2019 Nov 28.
: Although more than two decades are already passed from the first description of this technique, the debate remains open on the role of self-expanding metal stents (SEMS) placement in the management of malignant bowel obstruction (MBO). According to most recent data, SEMS placement is considered a safe and effective alternative treatment as a bridge to surgery(BTS). In addition, stent placement should be considered as primary option for palliative treatment of obstructing cancer.: Current status, indication, technique, oncological outcomes, advantages, and risks of SEMS placement in MBO were reviewed.: The placement of colonic SEMS for palliation and for BTS in patients with MBO has been increasingly reported and it seems to have several advantages over emergency surgery. Substantial concerns of tumor seeding following SEMS placement, especially in case of perforation, have been raised in numerous studies. Actually, no significant differences are reported in oncologic long-term survival between patients undergoing stent placement as a BTS and those undergoing emergency surgery. Considering all the mentioned factors, indication for colorectal stenting should be evaluated only in highly specialized centers, in the context of multidisciplinary approach where risks and benefits of stenting are carefully weighed, especially in the BTS setting.
尽管自首次描述该技术以来已经过去了二十多年,但在恶性肠梗阻 (MBO) 的管理中,自膨式金属支架 (SEMS) 放置的作用仍存在争议。根据最新数据,SEMS 放置被认为是一种安全有效的治疗选择,可作为手术 (BTS) 的桥梁。此外,支架放置应被视为梗阻性癌症姑息治疗的首选方案。本文综述了 MBO 中 SEMS 放置的当前状况、适应证、技术、肿瘤学结果、优势和风险。越来越多的报道称,在 MBO 患者中放置结肠 SEMS 用于姑息治疗和 BTS,并且它似乎比急诊手术具有许多优势。在许多研究中,人们对 SEMS 放置后肿瘤播散,尤其是穿孔后肿瘤播散的问题提出了大量关注。实际上,接受支架放置作为 BTS 治疗和接受急诊手术治疗的患者之间,在肿瘤学长期生存方面没有显著差异。考虑到所有这些因素,仅应在高度专业化的中心,在多学科方法的背景下评估结直肠支架的适应证,在仔细权衡支架治疗的风险和益处的情况下,尤其是在 BTS 环境下。