Key Laboratory for Tobacco Gene Resources, Tobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266101, China.
Graduate School of Chinese Academy of Agricultural Science, Beijing 100081, China.
Genes (Basel). 2019 Nov 26;10(12):973. doi: 10.3390/genes10120973.
E3 ubiquitin ligases are the most expanded components of the ubiquitin proteasome system (UPS). They mediate the recognition of substrates and later transfer the ubiquitin (Ub) of the system. Really Interesting New Gene (RING) finger proteins characterized by the RING domain, which contains 40-60 residues, are thought to be E3 ubiquitin ligase. RING-finger proteins play significant roles in plant growth, stress resistance, and signal transduction. In this study, we mainly describe the structural characteristics, classifications, and subcellular localizations of RING-finger proteins, as well the physiological processes of RING-finger proteins in plant growth and development. We also summarize the functions of plant RING-finger proteins in plant stress resistance. Finally, further research on plant RING-finger proteins is suggested, thereby establishing a strong foundation for the future study of plant RING-finger proteins.
E3 泛素连接酶是泛素蛋白酶体系统 (UPS) 中扩展最丰富的成分。它们介导底物的识别，然后将系统的泛素 (Ub) 转移。以 RING 结构域为特征的 Really Interesting New Gene (RING) 指蛋白，其包含 40-60 个残基，被认为是 E3 泛素连接酶。RING 指蛋白在植物生长、抗逆性和信号转导中发挥重要作用。在本研究中，我们主要描述了 RING 指蛋白的结构特征、分类和亚细胞定位，以及 RING 指蛋白在植物生长发育中的生理过程。我们还总结了植物 RING 指蛋白在植物抗逆性方面的功能。最后，对植物 RING 指蛋白的进一步研究提出了建议，从而为植物 RING 指蛋白的未来研究奠定了坚实的基础。
