Campochiaro P A, Conway B P
Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville 22908.
Arch Ophthalmol. 1988 Oct;106(10):1409-13. doi: 10.1001/archopht.1988.01060140573025.
We have followed five patients, each of whom had a solitary unilateral vascular mass of the sensory retina. The lesions were white or pink and often had hemorrhage and exudate on their surface or surrounding area. They appeared to be acquired, as three of the five patients were specifically noted to have normal fundi at some time before presentation. Fluorescein angiography and angioscopy demonstrated the masses to be composed of numerous vessels supplied by the retinal circulation. Slow growth was documented in one patient. Visual loss was variable and was due to leakage-related complications, including exudative detachment, recurrent vitreous hemorrhage, and cystoid macular edema. Four patients were treated with cryopexy, and in all four, this successfully caused involution of the lesions. Two patients had improvement in vision after treatment: one had stabilization, and one had deterioration. This report provides support for the existence of a distinct entity that we have called hemangiomalike mass of the retina, since no histopathologic evidence is yet available (to our knowledge). It also supports the use of judicious cryopexy to lesions associated with visual loss.
我们对5例患者进行了随访，每例患者的感觉视网膜均有一个孤立的单侧血管性肿块。病变呈白色或粉红色，表面或周围常有出血和渗出。这些病变似乎是后天获得的，因为5例患者中有3例在就诊前的某个时间点眼底检查明确显示正常。荧光素血管造影和血管内镜检查显示，肿块由视网膜循环供血的众多血管组成。有1例患者记录到肿块生长缓慢。视力丧失情况各异，原因是与渗漏相关的并发症，包括渗出性视网膜脱离、反复玻璃体积血和黄斑囊样水肿。4例患者接受了冷冻治疗，所有4例患者的病变均成功消退。2例患者治疗后视力有所改善：1例视力稳定，1例视力恶化。本报告支持一种我们称为视网膜血管瘤样肿块的独特实体的存在，因为目前尚无（据我们所知）组织病理学证据。它还支持对与视力丧失相关的病变谨慎使用冷冻治疗。
