Department of Veterinary Medicine, Agricultural College, Guangdong Ocean University, Zhanjiang, 524088, Guangdong, China.
Department of Animal Science, Agricultural College, Guangdong Ocean University, Zhanjiang, 524088, Guangdong, China.
J Therm Biol. 2019 Dec;86:102449. doi: 10.1016/j.jtherbio.2019.102449. Epub 2019 Nov 2.
Heat stress induces oxidative stress, and reduces antioxidant defenses of birds, which may affect poultry-production performance. Dietary antioxidants may protect against heat stress. We evaluated the effect of increasing concentrations of dietary curcumin on antioxidant parameters of hens under high-temperature conditions for nine weeks. Roman laying hens (n = 336, 22 weeks old, 1420 g weight) were divided into three treatment groups. The first group served as a thermo-neutral control (kept at 25 ± 1 °C). The second group was exposed to high temperatures (32 ± 1 °C, 6 h/day), and fed a basal diet. The third group was further divided into five groups, and all were exposed to high temperatures (32 ± 1 °C, 6 h/day) and provided a basal diet supplemented with 100, 150, 200, 250, 300 mg/kg curcumin (H1, H2, H3, H4, H5). All treatments included four replicates of 12 hens. Total superoxide dismutase (SOD) activity was significantly higher in H2 and H3 groups, and total antioxidant capacity (T-AOC) was higher in H2, H3, and H5 groups. Catalase (CAT) and glutathione peroxidase (GSH-Px) activities were significantly higher in the H3 group. Malondialdehyde concentrations were lower in curcumin supplemented hens compared to control groups hens. Hens in all curcumin treatment groups had slightly (but non-significantly) higher activities of CAT, SOD, GSH-Px, and T-AOC in liver, heart, and lung tissues, compared to heat stressed control group. It is concluded that dietary curcumin given to laying hens under heat stress may enhance their antioxidant status, and ameliorate stressful environmental conditions.
热应激会导致氧化应激，并降低鸟类的抗氧化防御能力，这可能会影响家禽生产性能。膳食抗氧化剂可能有助于抵抗热应激。我们评估了在高温条件下，日粮中添加不同浓度姜黄素对母鸡抗氧化参数的影响，为期 9 周。罗曼蛋鸡（n=336，22 周龄，体重 1420g）分为 3 个处理组。第一组作为热中性对照组（保持在 25±1°C）。第二组暴露于高温（32±1°C，每天 6 小时），并饲喂基础日粮。第三组进一步分为 5 组，均暴露于高温（32±1°C，每天 6 小时），并饲喂基础日粮，同时添加 100、150、200、250、300mg/kg 姜黄素（H1、H2、H3、H4、H5）。所有处理组包括 4 个 12 只母鸡的重复。H2 和 H3 组的总超氧化物歧化酶（SOD）活性显著升高，H2、H3 和 H5 组的总抗氧化能力（T-AOC）升高。H3 组的过氧化氢酶（CAT）和谷胱甘肽过氧化物酶（GSH-Px）活性显著升高。与对照组相比，添加姜黄素的母鸡的丙二醛浓度较低。与热应激对照组相比，所有添加姜黄素处理组的母鸡肝脏、心脏和肺组织中的 CAT、SOD、GSH-Px 和 T-AOC 活性略高（但无统计学意义）。综上所述，在热应激下给蛋鸡饲喂姜黄素可能会增强其抗氧化状态，改善应激环境条件。
