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糖尿病患者中合并抑郁症的患病率:观察性研究的荟萃分析。

The prevalence of comorbid depression in patients with diabetes: A meta-analysis of observational studies.

作者信息

Pashaki Mahdieh Sedighi, Mezel Jamal Asad, Mokhtari Zahra, Gheshlagh Reza Ghanei, Hesabi Parisa Shahbazi, Nematifard Taban, Khaki Soore

机构信息

Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of General Education, College of Education and Languages, Lebanese French University, Erbil, Kurdistan, Iraq.

出版信息

Diabetes Metab Syndr. 2019 Nov-Dec;13(6):3113-3119. doi: 10.1016/j.dsx.2019.11.003. Epub 2019 Nov 14.

DOI:10.1016/j.dsx.2019.11.003
PMID:31790965
Abstract

Depression is one of the most common psychiatric disorders in patients with diabetes, which can exacerbate and accelerate adverse diabetes complaints by reducing self-care behaviors and medication adherence. The purpose of this study is to estimate the prevalence of depression in Iranian patients with diabetes. The search was conducted in the databases of Scientific Information Database (SID), MagIran, PubMed, Scopus, Web of Science, and Google Scholar. The following keywords and their possible combinations were used: depressive disorder, major depressive disorder, dysthymic disorder, diabetes mellitus and Iran. Heterogeneity between studies was examined with I. The data were analyzed using the meta-analysis method and random-effects model with Stata version 11.0. The analysis of 37 selected articles with a total sample size of 7849 indicated that the overall prevalence of depression in Iranian patients with diabetes was 54% (95% CI: 47.32-60.70). In addition, the prevalence of depression in women (56.25%; 95% CI: 48.83-63.68) was higher than that of men (41.05%; 95% CI: 32.74-49.36). The results showed that there was no relationship between the prevalence of depression and publication year (0.249), sample size (p = 0.529), and mean age of the subjects (p = 0.330). More than half of the patients with diabetes suffer from depression. Identification and treatment of these patients can be an important step in controlling and delaying the diabetes complication.

摘要

抑郁症是糖尿病患者中最常见的精神障碍之一,它会通过减少自我护理行为和药物依从性来加剧并加速糖尿病的不良症状。本研究的目的是评估伊朗糖尿病患者中抑郁症的患病率。检索工作在科学信息数据库(SID)、MagIran、PubMed、Scopus、科学网和谷歌学术等数据库中进行。使用了以下关键词及其可能的组合:抑郁症、重度抑郁症、心境恶劣障碍、糖尿病和伊朗。采用I检验研究间的异质性。使用Stata 11.0软件,采用Meta分析方法和随机效应模型对数据进行分析。对37篇选定文章进行分析,总样本量为7849,结果表明伊朗糖尿病患者中抑郁症的总体患病率为54%(95%可信区间:47.32 - 60.70)。此外,女性抑郁症患病率(56.25%;95%可信区间:48.83 - 63.68)高于男性(41.05%;95%可信区间:32.74 - 49.36)。结果显示,抑郁症患病率与发表年份(0.249)、样本量(p = 0.529)和受试者平均年龄(p = 0.330)之间均无关联。超过一半的糖尿病患者患有抑郁症。识别和治疗这些患者可能是控制和延缓糖尿病并发症的重要一步。

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