Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA, USA.
Headache. 2020 Jan;60(1):178-189. doi: 10.1111/head.13716. Epub 2019 Dec 2.
To review the published findings relevant to migraine and driving performance, with an intent to encourage discussion on research which may broaden understanding in this area and help educate healthcare providers and their patients.
Motor vehicle crashes result in more than 35,000 deaths and more than 2 million injuries annually in the United States. Migraine is one of the most prevalent diseases in the world, and many symptoms associated with migraine attacks have the potential to negatively influence driving ability.
We reviewed the published findings related to migraine and driving performance. Study findings relevant to symptoms of migraine and their potential effect on driving were also reviewed. This required a more expansive exploration of the literature beyond migraine, for example, review of the literature relating to the effect of pain, sleepiness, visual disturbances, or vertigo on driving. Finally, the potential effects of treatment for migraine on driving were reviewed.
Literature on the effect of migraine on driving performance is sparse and, in general published studies on the topic have a number of limitations. Based on review of the literature pertaining to other disorders, it seems feasible that some symptoms occurring as part of the migraine attack could impact driving performance, although formal study in this area is lacking. Many of the approved treatments for migraine have the potential to impact driving, yet this has not been specifically studied, and the extent to which these risks are communicated to patients is not clear.
The impact of migraine on driving performance has been largely neglected, with few studies specifically designed to address the topic, and relevant studies were generally small with limited control of confounders. This area requires more focus, given a potential for impact on road safety.
回顾与偏头痛和驾驶表现相关的已发表研究结果，旨在鼓励对可能拓宽该领域理解并有助于教育医疗保健提供者及其患者的研究进行讨论。
在美国，每年因机动车事故导致超过 35000 人死亡和超过 200 万人受伤。偏头痛是世界上最常见的疾病之一，与偏头痛发作相关的许多症状都有可能对驾驶能力产生负面影响。
我们回顾了与偏头痛和驾驶表现相关的已发表研究结果。还回顾了与偏头痛症状及其对驾驶的潜在影响相关的研究结果。这需要对偏头痛以外的文献进行更广泛的探索，例如，对与疼痛、嗜睡、视觉障碍或眩晕对驾驶的影响相关的文献进行综述。最后，还回顾了偏头痛治疗对驾驶的潜在影响。
关于偏头痛对驾驶表现影响的文献很少，而且关于该主题的已发表研究通常存在许多局限性。根据对其他疾病相关文献的回顾，偏头痛发作中出现的某些症状似乎有可能影响驾驶表现，尽管该领域缺乏正式研究。许多批准用于治疗偏头痛的药物都有可能影响驾驶，但这尚未得到具体研究，并且这些风险向患者传达的程度尚不清楚。
偏头痛对驾驶表现的影响在很大程度上被忽视了，很少有专门针对该主题的研究，而相关研究通常规模较小，对混杂因素的控制有限。鉴于对道路安全的潜在影响，该领域需要更多关注。
