Cernelc P, Kralj J, Cernelc D
Int J Pediatr Otorhinolaryngol. 1979 Sep;1(2):157-64. doi: 10.1016/0165-5876(79)90008-9.
This investigation was carried out to determine the immunological function of the human tonsils, especially the role of lymphocytes of atopic and non-atopic children. An E- and EAC-rosette forming technique is introduced, with semiquantitative evaluation of T and B lymphocytes in the peripheral blood of 56 normal subjects, 28 atopic and 5 non-atopic children of both sexes and different ages. The percentage of T and B lymphocytes in removed palatine tonsils in 28 atopic and 5 non-atopic children was calculated. The percentage of rosette-forming cells in E and EAC suspensions appeared to be independent of age and sex. The percentage of T lymphocytes in peripheral blood was significantly higher than in the palatine tonsils, whereas the percentage of B lymphocytes was significantly higher in the tonsils of atopic and non-atopic children than in the peripheral blood. The mean percentage of B lymphocytes in the tonsils of atopic children was significantly higher than in non-atopic children. The percentage of B lymphocytes was found to be significantly higher in hypertrophic than in small tonsils. Also, in the tonsils with adhesions there was a statistically significantly higher percentage of EAC rosettes than in the tonsils free of adhesions. The percentage of T lymphocytes was statistically significantly higher in the small tonsils.
本研究旨在确定人类扁桃体的免疫功能，尤其是特应性和非特应性儿童淋巴细胞的作用。引入了E花环和EAC花环形成技术，对56名正常受试者、28名不同年龄和性别的特应性儿童以及5名非特应性儿童的外周血中的T淋巴细胞和B淋巴细胞进行半定量评估。计算了28名特应性儿童和5名非特应性儿童切除的腭扁桃体中T淋巴细胞和B淋巴细胞的百分比。E和EAC悬液中花环形成细胞的百分比似乎与年龄和性别无关。外周血中T淋巴细胞的百分比显著高于腭扁桃体，而特应性和非特应性儿童扁桃体中B淋巴细胞的百分比显著高于外周血。特应性儿童扁桃体中B淋巴细胞的平均百分比显著高于非特应性儿童。发现肥大扁桃体中B淋巴细胞的百分比显著高于小扁桃体。此外，有粘连的扁桃体中EAC花环的百分比在统计学上显著高于无粘连的扁桃体。小扁桃体中T淋巴细胞的百分比在统计学上显著更高。
