Mosquera-Perez Regina, Fernández-Olavarria Ana, Diaz-Sanchez Rosa-Maria, Gutierrez-Perez José-Luis, Serrera-Figallo María-Ángeles, Torres-Lagares Daniel
DDS. Department of Stomatology, Faculty of Dentistry, University of Seville (US), Seville, Spain.
MD, PhD. Department of Stomatology, Faculty of Dentistry, University of Seville (US), Seville, Spain.
J Clin Exp Dent. 2019 Dec 1;11(12):e1181-e1189. doi: 10.4317/jced.56571. eCollection 2019 Dec.
Considering the structural loss that occurs after surgical procedures for cystic and tumoral pathology, in periodontitis, as well as the maxillary atrophy that determines the rehabilitation with dental implants, it is imperative to find satisfactory solutions. The opportunity provided by the findings in stem cells is a recent introduction in the field of oral surgery, based on the regenerative potential that these cells possess in order to restore defects at different levels of the oral cavity. The aim of this systematic review is to discover the real applications that stem cells may have in our treatments in the near future.
We made a systematic review of the literature on the subject of stem cells to know the publications relating to them in the field of oral surgery since 2000. PRISMA statement was accomplished, as its official flow chart is used.
This article draws clinical conclusions from basic research and those conducted in the first clinical cases to apply them in a short period of time to our patients in order to achieve excellence in regenerative therapies.
To summarize, stem cells may be a turning point in tissue regeneration, though the major challenge is to overcome the remaining obstacles before they become a realistic therapeutic alternative. Stem cells, oral surgery, cell therapy, regeneration.
考虑到针对囊性和肿瘤性病变的外科手术、牙周炎所导致的结构丧失，以及决定采用牙种植体进行修复的上颌骨萎缩，找到令人满意的解决方案势在必行。干细胞研究成果所带来的契机是口腔外科领域的一项最新进展，这基于这些细胞所具有的在口腔不同层面修复缺损的再生潜能。本系统评价的目的是探寻干细胞在不久的将来于我们的治疗中可能具有的实际应用。
我们对关于干细胞主题的文献进行了系统评价，以了解自2000年以来口腔外科领域与之相关的出版物。完成了PRISMA声明，并使用了其官方流程图。
本文从基础研究以及在首批临床病例中开展的研究得出临床结论，以便在短时间内将其应用于我们的患者，从而在再生治疗方面实现卓越成效。
总而言之，干细胞可能是组织再生的一个转折点，不过主要挑战在于在它们成为一种切实可行的治疗选择之前克服尚存的障碍。干细胞、口腔外科、细胞治疗、再生。
