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经典型卡波西肉瘤在包皮环切阴茎上的非典型表现,呈现为溃疡性结节,人疱疹病毒8(HHV8)阳性,仅通过局部切除成功治愈。

Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision.

作者信息

Alamri Abdulaziz, Adiga B K

机构信息

1College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.

2Department of Pathology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.

出版信息

Infect Agent Cancer. 2019 Dec 2;14:45. doi: 10.1186/s13027-019-0261-6. eCollection 2019.

Abstract

INTRODUCTION

Although the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital KS is rare, particularly in people without risk factors for HIV infection. Isolated penile KS is an unusual manifestation, especially as solitary nodule with ulceration, in HIV seronegative patient.

CASE PRESENTATION

We report such a case of Kaposi sarcoma showing HHV-8 positivity in an elderly male Arabian patient with a delay in prompt diagnosis, but treated successfully with 3 3 years follow-up after limited local surgical excision.

CONCLUSION

The general practitioners, venereologists and urologists should think of KS as a possibility in such lesion and consider early biopsy.

摘要

引言

尽管卡波西肉瘤(KS)是艾滋病的定义性疾病之一,在几乎三分之一的CD4细胞计数低的HIV感染患者中可见,但在HIV血清阴性者中也并不罕见,不过生殖器KS很少见,尤其是在没有HIV感染危险因素的人群中。孤立性阴茎KS是一种不寻常的表现,特别是在HIV血清阴性患者中表现为伴有溃疡的孤立结节。

病例报告

我们报告了这样一例卡波西肉瘤病例,该病例在一名老年阿拉伯男性患者中显示HHV-8阳性,诊断延迟,但在有限的局部手术切除后成功治疗并进行了3年随访。

结论

全科医生、性病学家和泌尿科医生在遇到此类病变时应考虑到KS的可能性,并考虑早期活检。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff9/6889700/bc69e8efdf05/13027_2019_261_Fig1_HTML.jpg

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