• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

经典型卡波西肉瘤在包皮环切阴茎上的非典型表现,呈现为溃疡性结节,人疱疹病毒8(HHV8)阳性,仅通过局部切除成功治愈。

Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision.

作者信息

Alamri Abdulaziz, Adiga B K

机构信息

1College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.

2Department of Pathology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.

出版信息

Infect Agent Cancer. 2019 Dec 2;14:45. doi: 10.1186/s13027-019-0261-6. eCollection 2019.

DOI:10.1186/s13027-019-0261-6
PMID:31827596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6889700/
Abstract

INTRODUCTION

Although the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital KS is rare, particularly in people without risk factors for HIV infection. Isolated penile KS is an unusual manifestation, especially as solitary nodule with ulceration, in HIV seronegative patient.

CASE PRESENTATION

We report such a case of Kaposi sarcoma showing HHV-8 positivity in an elderly male Arabian patient with a delay in prompt diagnosis, but treated successfully with 3 3 years follow-up after limited local surgical excision.

CONCLUSION

The general practitioners, venereologists and urologists should think of KS as a possibility in such lesion and consider early biopsy.

摘要

引言

尽管卡波西肉瘤(KS)是艾滋病的定义性疾病之一,在几乎三分之一的CD4细胞计数低的HIV感染患者中可见,但在HIV血清阴性者中也并不罕见,不过生殖器KS很少见,尤其是在没有HIV感染危险因素的人群中。孤立性阴茎KS是一种不寻常的表现,特别是在HIV血清阴性患者中表现为伴有溃疡的孤立结节。

病例报告

我们报告了这样一例卡波西肉瘤病例,该病例在一名老年阿拉伯男性患者中显示HHV-8阳性,诊断延迟,但在有限的局部手术切除后成功治疗并进行了3年随访。

结论

全科医生、性病学家和泌尿科医生在遇到此类病变时应考虑到KS的可能性,并考虑早期活检。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff9/6889700/bc69e8efdf05/13027_2019_261_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff9/6889700/bc69e8efdf05/13027_2019_261_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ff9/6889700/bc69e8efdf05/13027_2019_261_Fig1_HTML.jpg

相似文献

1
Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision.经典型卡波西肉瘤在包皮环切阴茎上的非典型表现,呈现为溃疡性结节,人疱疹病毒8(HHV8)阳性,仅通过局部切除成功治愈。
Infect Agent Cancer. 2019 Dec 2;14:45. doi: 10.1186/s13027-019-0261-6. eCollection 2019.
2
Isolated Kaposi Sarcoma in two HIV negative patients.两名HIV阴性患者的孤立性卡波西肉瘤
J Dermatol Case Rep. 2011 Jun 6;5(2):24-6. doi: 10.3315/jdcr.2011.1067.
3
Human herpesvirus 8 seropositivity and risk of Kaposi's sarcoma and other acquired immunodeficiency syndrome-related diseases.人类疱疹病毒8型血清阳性与卡波西肉瘤及其他获得性免疫缺陷综合征相关疾病的风险
J Natl Cancer Inst. 1999 Sep 1;91(17):1468-74. doi: 10.1093/jnci/91.17.1468.
4
Penile Kaposi Sarcoma as an initial manifestation of HIV infection: A case report and literature review.阴茎卡波西肉瘤作为HIV感染的首发表现:一例病例报告及文献综述
IDCases. 2022 Jul 19;29:e01576. doi: 10.1016/j.idcr.2022.e01576. eCollection 2022.
5
Localization of human herpesvirus type 8 (HHV-8) in the Kaposi's sarcoma tissues and the semen specimens of HIV-1 infected and uninfected individuals by utilizing in situ polymerase chain reaction.通过原位聚合酶链反应对人疱疹病毒8型(HHV-8)在卡波西肉瘤组织以及HIV-1感染和未感染个体的精液标本中的定位。
J Reprod Immunol. 1998 Dec;41(1-2):149-60. doi: 10.1016/s0165-0378(98)00055-2.
6
Penile Kaposi's sarcomas in a circumcised and HIV-seronegative patient.一名包皮环切且HIV血清学阴性患者的阴茎卡波西肉瘤。
Int J Urol. 2006 Mar;13(3):318-20. doi: 10.1111/j.1442-2042.2006.01282.x.
7
A Challenging Case of Kaposi Sarcoma Inflammatory Cytokine Syndrome.卡波西肉瘤炎性细胞因子综合征的一个具有挑战性的病例。
Cureus. 2023 Jul 20;15(7):e42218. doi: 10.7759/cureus.42218. eCollection 2023 Jul.
8
Isolated penile Kaposi's sarcoma in a HIV-positive patient stable on treatment for three years.一名接受治疗三年病情稳定的HIV阳性患者出现孤立性阴茎卡波西肉瘤。
Int J STD AIDS. 2014 Jul;25(8):607-10. doi: 10.1177/0956462413517494. Epub 2014 Feb 3.
9
Primary Classic Kaposi's Sarcoma of the Penis in an HIV-Negative Patient.
Korean J Urol. 2010 Nov;51(11):803-6. doi: 10.4111/kju.2010.51.11.803. Epub 2010 Nov 17.
10
Fatal pulmonary Kaposi sarcoma in an HIV seronegative AIDS patient.一名HIV血清阴性艾滋病患者的致命性肺卡波西肉瘤
Clin Respir J. 2017 Nov;11(6):1040-1044. doi: 10.1111/crj.12463. Epub 2016 Mar 2.

引用本文的文献

1
Primary Classic Penile Kaposi's Sarcoma in a Middle Age Circumcised HIV-Negative Patient: Presentation of an Unusual Case.一名中年包皮环切的HIV阴性患者的原发性经典阴茎卡波西肉瘤:罕见病例报告
Sisli Etfal Hastan Tıp Bul. 2024 Jun 28;58(2):241-243. doi: 10.14744/SEMB.2023.46034. eCollection 2024.
2
Tumor Lysis Syndrome: Introduction of a Cutaneous Variant and a New Classification System.肿瘤溶解综合征:一种皮肤变异型及新分类系统的介绍
Cureus. 2021 Mar 11;13(3):e13816. doi: 10.7759/cureus.13816.
3
Primary Kaposi sarcoma of the glans: A rare case in an HIV-negative patient.

本文引用的文献

1
Epidemiology of Kaposi sarcoma: review and description of the nonepidemic variant.卡波西肉瘤的流行病学:回顾与非流行型变体的描述。
Int J Dermatol. 2019 May;58(5):538-542. doi: 10.1111/ijd.14080. Epub 2018 Jun 11.
2
Non-AIDS-related Kaposi's sarcoma: A single-institution experience.非艾滋病相关的卡波西肉瘤:单机构经验
World J Clin Oncol. 2013 May 10;4(2):52-7. doi: 10.5306/wjco.v4.i2.52.
3
Kaposi sarcoma.卡波西肉瘤。
阴茎头原发性卡波西肉瘤:1例HIV阴性患者的罕见病例。
Clin Case Rep. 2020 Apr 13;8(7):1134-1137. doi: 10.1002/ccr3.2838. eCollection 2020 Jul.
Arch Pathol Lab Med. 2013 Feb;137(2):289-94. doi: 10.5858/arpa.2012-0101-RS.
4
Localized genital Kaposi sarcoma.局限性生殖器卡波西肉瘤。
Ann Saudi Med. 1994 Nov;14(6):517-8. doi: 10.5144/0256-4947.1994.517.
5
HIV - associated and non - HIV associated types of Kaposi's sarcoma in an African population in Tanzania. Status of immune suppression and HHV-8 seroprevalence.坦桑尼亚一个非洲人群中与HIV相关和非HIV相关的卡波西肉瘤类型。免疫抑制状况和HHV-8血清阳性率。
Eur J Dermatol. 2006 Nov-Dec;16(6):677-82.
6
Primary classic Kaposi's sarcoma of the penis: report of a case and review.阴茎原发性经典型卡波西肉瘤:1例报告及文献复习
J Eur Acad Dermatol Venereol. 2003 May;17(3):320-3. doi: 10.1046/j.1468-3083.2003.00747.x.
7
Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient: first report of a solitary lesion.一名HIV阴性患者的8型疱疹病毒相关阴茎卡波西肉瘤:孤立性病变的首例报告
Am J Dermatopathol. 2003 Feb;25(1):28-31. doi: 10.1097/00000372-200302000-00006.
8
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma.在艾滋病相关的卡波西肉瘤中鉴定出疱疹病毒样DNA序列。
Science. 1994 Dec 16;266(5192):1865-9. doi: 10.1126/science.7997879.
9
Diagnostic implications of genital Kaposi's sarcoma.生殖器卡波西肉瘤的诊断意义
East Afr Med J. 1989 Aug;66(8):499-502.
10
Kaposi's sarcoma of the penis in patients with acquired immunodeficiency syndrome.获得性免疫缺陷综合征患者的阴茎卡波西肉瘤
J Urol. 1989 Dec;142(6):1475-7. doi: 10.1016/s0022-5347(17)39129-2.