Jiang Rong-San, Lu Yu-Yu
Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan.
Case Rep Otolaryngol. 2019 Nov 16;2019:1069741. doi: 10.1155/2019/1069741. eCollection 2019.
Head trauma is one of the most common etiologies of olfactory dysfunction. It is difficult to use either the olfactory function test or magnetic resonance imaging to directly assess the course of damage to olfactory nerves. Thallium-201 (Tl) olfacto-scintigraphy has been shown to be an able means for objectively assessing the olfactory nerve transport function. It is expected to be used to evaluate olfactory nerve regeneration after damage to the olfactory nerves. However, no such result has been reported. We present a patient who lost his olfactory function after experiencing head trauma. When his olfactory function remained anosmic, a Tl olfacto-scintigraphy showed no migration of Tl from the nasal mucosa to the olfactory bulb. After treatment with medicines and olfactory training, his olfactory function improved. A second Tl olfacto-scintigraphy showed an increased migration of Tl from the nasal mucosa to the olfactory bulb.
头部外伤是嗅觉功能障碍最常见的病因之一。使用嗅觉功能测试或磁共振成像直接评估嗅神经的损伤过程都很困难。铊-201（Tl）嗅觉闪烁扫描已被证明是客观评估嗅神经传输功能的有效手段。它有望用于评估嗅神经损伤后的再生情况。然而，尚未有此类结果的报道。我们报告一位头部外伤后失去嗅觉功能的患者。当他的嗅觉功能仍为嗅觉丧失时，一次铊嗅觉闪烁扫描显示铊没有从鼻粘膜迁移至嗅球。经过药物治疗和嗅觉训练后，他的嗅觉功能有所改善。第二次铊嗅觉闪烁扫描显示从鼻粘膜至嗅球的铊迁移增加。
