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2009年4月至9月澳大利亚维多利亚州甲型H1N1流感大流行监测

Pandemic H1N1 influenza surveillance in Victoria, Australia, April - September, 2009.

作者信息

Fielding Je, Higgins N, Gregory Je, Grant Ka, Catton Mg, Bergeri I, Lester Ra, Kelly Ha

机构信息

Victorian Department of Health, Melbourne, Australia.

出版信息

Euro Surveill. 2009 Oct 22;14(42):19368. doi: 10.2807/ese.14.42.19368-en.

Abstract

Victoria was the first Australian state to report widespread transmission of pandemic H1N1 2009 influenza. Notifiable laboratory-confirmed influenza and a general practitioner sentinel surveillance system measuring influenza-like illness (ILI), including laboratory confirmation of influenza as the cause of ILI, were used to assess the pandemic. The pandemic influenza A(H1N1)v virus quickly became the dominant circulating strain and notification rates were highest in children and young adults. Despite a high number of notified cases, comparison of ILI rates suggested the season peaked in late June, was similar in magnitude to 2003 and 2007 and less severe than 1997. The majority of clinical presentations were mild, but one quarter of hospitalised cases required admission to intensive care. Given the low proportion of imported cases in the Victorian pandemic, the rapid increase in cases with no travel history and the low median age of cases notified during the phases of intense surveillance, we suggest there may have been silent importations of pandemic virus into Victoria before the first case was recognised. The usefulness of a general practitioner sentinel surveillance system to provide a comparable assessment of influenza and ILI activity over time was clearly demonstrated, and the need for similar hospital and mortality surveillance systems for influenza in Victoria was highlighted.

摘要

维多利亚州是澳大利亚首个报告2009年甲型H1N1大流行性流感广泛传播的州。利用法定报告的实验室确诊流感病例以及一个测量流感样疾病(ILI)的全科医生哨点监测系统(包括对导致ILI的流感进行实验室确诊)来评估此次大流行情况。甲型H1N1v大流行性流感病毒迅速成为主要的流行毒株,儿童和年轻人中的报告率最高。尽管报告病例数量众多,但ILI发病率的比较表明,该季节在6月下旬达到高峰,规模与2003年和2007年相似,且比1997年的情况要轻。大多数临床表现为轻症,但四分之一的住院病例需要入住重症监护病房。鉴于维多利亚州大流行期间输入病例所占比例较低、无旅行史病例迅速增加以及在严密监测阶段报告病例的年龄中位数较低,我们认为在首例病例被确认之前,大流行病毒可能已悄然输入维多利亚州。全科医生哨点监测系统在对流感和ILI活动进行长期可比评估方面的实用性得到了明确证明,同时也凸显了在维多利亚州建立类似的流感医院监测和死亡率监测系统的必要性。

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