Zhang Tengjiao, Zhang Jingjing, Qu Zongyang, Hua Zhen, Sun Yanxia
Department of Anesthesiology, Beijing Hospital, National Centre of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China.
Department of Anesthesiology, The People's Hospital of Jizhou District, Tianjin, Tianjin, 301900, China.
Sci Rep. 2025 Jul 1;15(1):21993. doi: 10.1038/s41598-025-03958-w.
The effectiveness of erector spinae plane block (ESPB) in preventing chronic pain after posterior lumbar surgery remains controversial. The primary hypothesis of this study was that ESPB reduces the incidence of chronic pain for 3 months after posterior lumbar surgery. In this prospective, randomized, parallel-group study, a total of 120 patients who underwent open posterior lumbar decompression surgery under general anesthesia were randomized into two groups. The ESPB group underwent preoperative bilateral ESPB, and the control group did not receive the block. The primary outcome was the incidence of chronic pain at 3 months after surgery. The secondary outcomes included postoperative morphine consumption, time to first ambulation after surgery, length of hospital stay and incidence of chronic pain at 6 months after surgery. At 3 months, chronic pain was reported in 21/56 (37.5%) and 28/58 (48.3%) patients in the ESPB and control groups, respectively (OR = 1.6; 95% CI, 0.7-3.3; p = 0.245). The ESPB group had less postoperative morphine consumption (p < 0.001) and a shorter time to first ambulation after surgery (p = 0.006) than the control group did. The length of hospital stay was similar. There was also no difference in the incidence of chronic pain at 6 months. ESPB did not reduce the incidence of chronic pain after posterior lumbar surgery, but it did facilitate early recovery after surgery.
竖脊肌平面阻滞(ESPB)预防腰椎后路手术后慢性疼痛的有效性仍存在争议。本研究的主要假设是,ESPB可降低腰椎后路手术后3个月慢性疼痛的发生率。在这项前瞻性、随机、平行组研究中,共有120例在全身麻醉下接受开放性腰椎后路减压手术的患者被随机分为两组。ESPB组在术前接受双侧ESPB,对照组未接受该阻滞。主要结局是术后3个月慢性疼痛的发生率。次要结局包括术后吗啡用量、术后首次下床活动时间、住院时间以及术后6个月慢性疼痛的发生率。在3个月时,ESPB组和对照组分别有21/56(37.5%)和28/58(48.3%)的患者报告有慢性疼痛(OR = 1.6;95%CI,0.7 - 3.3;p = 0.245)。ESPB组术后吗啡用量少于对照组(p < 0.001),术后首次下床活动时间短于对照组(p = 0.006)。住院时间相似。6个月时慢性疼痛的发生率也没有差异。ESPB并不能降低腰椎后路手术后慢性疼痛的发生率,但确实有助于术后早期恢复。